Reanalysis datasets provide a reliable reanalysis of climate input data for hydrological models in regions characterized by limited weather station coverage. In this paper, the accuracy of precipitation, the maximum and minimum temperatures of four reanalysis datasets, the China Meteorological Assimilation Driving Datasets for the SWAT model (CMADS), time-expanded climate forecast system reanalysis (CFSR+), the European Centre for Medium-Range Weather Forecast Reanalysis (ERA). and the China Meteorological Forcing Dataset (CMFD), were evaluated by using data from 28 ground-based observations (OBs) in the Source of the Yangtze and Yellow Rivers (SYYR) region and were used as input data for the SWAT model for runoff simulation and performance evaluation, respectively. And, finally, the CMADS was optimized using Integrated Calibrated Multi-Satellite Retrievals for Global Precipitation Measurement (AIMERG) data. The results show that CMFD is the most representative reanalysis data for precipitation characteristics in the SYYR region among the four reanalysis datasets evaluated in this paper, followed by ERA5 and CFSR, while CMADS performs satisfactorily for temperature simulations in this region, but underestimates precipitation. And we contend that the accuracy of runoff simulations is notably contingent upon the precision of daily precipitation within the reanalysis dataset. The runoff simulations in this region do not effectively capture the extreme runoff characteristics of the Yellow River and Yangtze River sources. The refinement of CMADS through the integration of AIMERG satellite precipitation data emerges as a potent strategy for enhancing the precision of runoff simulations. This research can provide a reference for selecting meteorological data products and optimization methods for hydrological process simulation in areas with few meteorological stations.