Apport de la polygraphie nocturne au diagnostic du syndrome de Pickwick

Abstract

The authors studied a series of 10 obese patients with respiratory failure referred for treatment because of sleep disorders and diurnal, sometimes uncontrollable, episodes of somnolence. 8 parameters were recorded in the polygraphie study performed during a night of hospitalization: electroencephalogram, electrocardiogram, electro-oculogram, chin electromyogram, thoracic movements, and nasal and buccal air flows. SaO₂ and transcutaneous PO₂ were recorded simultaneously. A sleep apnea syndrome was diagnosed in 6 of the 10 patients, whose apnea index was markedly above the limit of 5 apneas per hour. The apnea index was below 5 in the other 4 patients. Most patients with sleep apnea syndrome suffer from obstructive apneas of varying duration taking up as much as 48% of total sleep time. The cardiorespiratory effects of these events are apparent, with a drop in PO2 and SaO₂ and a decrease in heart rate at the end of apnea. Polygraphie studies seem useful in the diagnosis of the pickwickian syndrome. They allow the type of apnea and its effects to be specified and thus guide treatment

Obesity – hypoventilation syndrome

“…Для подтверждения диагноза «СОГ» проводятся такие исследования, как анализ газового состава артериальной крови (подтверждает наличие дневной гиперкапнии), развернутый клинический анализ крови (определение концентрации электролитов, креатинина, гормонов щитовидной железы), функциональные исследования (спирометрия, бодиплетизмография, диффузионный тест, а также тест на силу дыхательных мышц) [26], эхокардиография (Эхо-КГ), полисомнография, кардиореспираторный скрининг [27].…”