Appreciative inquiry (AI) has been used to promote positive change in different areas of organizational life. It is based on the 4D cycle which includes four distinct stages: discover, dream, design, and destiny. Organizational wellbeing is both a strategy and a responsibility, especially in recent times, when the line between work and life seems to be blurring, and there has been an increased concern about the role that work plays in the health and wellbeing of employees. AI is substantially different from other institutional analysis methodologies because it is not focused on solving problems, but on the positive aspects of organizational life and culture. This chapter presents the case of a private university in Puebla, Mexico, which has been promoting holistic programs to improve employees' wellbeing and happiness, reducing stress and other potential health problems through appreciative inquiry on what members dream, long for, and aspire in terms of better overall health. It is a descriptive study that presents a specific case.