Approaches of 3D printing in current drug delivery

Mohapatra, Snehamayee; Kar, Rajat Kumar; Biswal, Prasanta Kumar; Bindhani, Sabitri

doi:10.1016/j.sintl.2021.100146

Cited by 65 publications

(30 citation statements)

References 97 publications

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“…3D printed drug delivery systems have advantages, such as the ability to design customized drug products with high flexibility to select the shape, dose, and size of the dosage form to meet individual patient needs [56]. Drug delivery systems designed by 3D printing technology can lead to personalized drug dosing, complex drug release profiles and personalized topical drug delivery as novel applications [57]. Economidou et al [58] used SLA technology to design a microneedle array using a biocompatible resin for insulin delivery [Fig.…”

Section: Drug Deliverymentioning

confidence: 99%

Application of 3D Bioprinting Technology for Tissue Regeneration, Drug Evaluation, and Drug Delivery

Kim

Kwon

2023

Appl. Sci. Converg. Technol.

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To overcome the limitation of two-dimensional cell culture not being able to mimic the in vivo microenvironment, three-dimensional (3D) bioprinting technology for 3D cell culture has emerged as an innovative culture platform. 3D bioprinting technologies can be divided into five types: inkjet-based bioprinting, extrusion-based bioprinting, stereolithography bioprinting, laser-assisted bioprinting and digital laser processing-based bioprinting technology. The 3D printing strategies achieved through a combination of these technologies can be applied to develop tissue regeneration, drug evaluation and drug delivery systems. In addition, the choice of cells and biomaterials is an important factor in fabricating tissue/organ models. Biomaterials for 3D bioprinting can be divided into natural polymers (alginate, gelatin, collagen, chitosan, agarose, and hyaluronic acid) and synthetic polymers (polylactic acid, polyvinyl alcohol, polycaprolactone, polyethylene oxide and thermoplastic polyurethane). Depending on the goals of 3D bioprinting experiments, biomaterials can be used alone or in combination with various polymers. 3D bioprinting technology has the potential to be applied for personalized medicine, precision medicine and the fabrication of artificial tissue/organs.

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Section: Drug Deliverymentioning

confidence: 99%

Application of 3D Bioprinting Technology for Tissue Regeneration, Drug Evaluation, and Drug Delivery

Kim

Kwon

2023

Appl. Sci. Converg. Technol.

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“…As one of the most progressive innovations in pharmaceutical science, 3DP has become a revolutionary and powerful tool in the precise manufacturing of individually developed dosage forms, tissue engineering, pharmaceutical analysis, and disease modeling 145 . It allows a fast, efficient, and economical production of customized drug carriers with desirable shape, size, and structure from 3D computer data to provide personalized medication, various drug combinations, and complex drug release profiles.…”

Section: Application Of Biotechnology In Pharmaceutical Products Anal...mentioning

confidence: 99%

Emerging biotechnology applications in natural product and synthetic pharmaceutical analyses

Chen

Zhang

et al. 2022

Acta Pharmaceutica Sinica B

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“…Thus, validation is necessary to ensure the final product satisfies the safety requirements. [ 228 ] For the successful printing of complex structures, parameters such as nozzle size, printer type, and the physicochemical properties of the materials should be considered.…”

Section: Concerns and Challenges Of Photocurable 3d Printingmentioning

confidence: 99%

Recent Advances in 3D Printing of Photocurable Polymers: Types, Mechanism, and Tissue Engineering Application

Randhawa

Dutta

Ganguly

et al. 2022

Macromolecular Bioscience

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The conversion of liquid resin into solid structures upon exposure to light of a specific wavelength is known as photopolymerization. In recent years, photopolymerization‐based 3D printing has gained enormous attention for constructing complex tissue‐specific constructs. Due to the economic and environmental benefits of the biopolymers employed, photo‐curable 3D printing is considered an alternative method for replacing damaged tissues. However, the lack of suitable bio‐based photopolymers, their characterization, effective crosslinking strategies, and optimal printing conditions are hindering the extensive application of 3D printed materials in the global market. This review highlights the present status of various photopolymers, their synthesis, and their optimization parameters for biomedical applications. Moreover, a glimpse of various photopolymerization techniques currently employed for 3D printing is also discussed. Furthermore, various naturally derived nanomaterials reinforced polymerization and their influence on printability and shape fidelity are also reviewed. Finally, the ultimate use of those photopolymerized hydrogel scaffolds in tissue engineering is also discussed. Taken together, it is believed that photopolymerized 3D printing has a great future, whereas conventional 3D printing requires considerable sophistication, and this review can provide readers with a comprehensive approach to developing light‐mediated 3D printing for tissue‐engineering applications.

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Approaches of 3D printing in current drug delivery

Cited by 65 publications

References 97 publications

Application of 3D Bioprinting Technology for Tissue Regeneration, Drug Evaluation, and Drug Delivery

Application of 3D Bioprinting Technology for Tissue Regeneration, Drug Evaluation, and Drug Delivery

Emerging biotechnology applications in natural product and synthetic pharmaceutical analyses

Recent Advances in 3D Printing of Photocurable Polymers: Types, Mechanism, and Tissue Engineering Application

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