In this paper we introduce a q-generalization of Post-Widder operators Pn,q. We give a Voronovskaja-type approximation result and rate of that convergence. We also study approximation properties of Pn,q in a weighted space. We also show that the rates of convergence of these generalized operators to approximating function f as weight are at least so faster than that of the classical Post-Widder operators.