Aquagenic wrinkling of the palms: review of the literature

Abstract

Aquagenic wrinkling of the palms (AWP) is a rare dermatological disease characterized by development of rapid and excessive wrinkling and oedema of the palms and transient whitish or yellowish papules without erythema on the palmar surfaces after immersion in water. This phenomenon can be accompanied by pain and/or pruritus. The most common treatment of AWP involves aluminium-based topicals. This article discusses the associations, pathological mechanisms and treatment options of AWP.

Wood's light as a noval diagnostic tool in aquagenic keratoderma

“… 6 However, aluminium chloride solution has been shown to dramatically improve symptoms and signs in aquagnic keratoderma. 7 Other treatment options include injections of Botulinum toxin mainly if associated with hyperhidrosis. Medication‐induced cases can be treated with discontinuation of the culprit medication.…”

“…Topical treatments such as salicylic‐acid‐based products and urea‐containing creams showed variable results 6 . However, aluminium chloride solution has been shown to dramatically improve symptoms and signs in aquagnic keratoderma 7 . Other treatment options include injections of Botulinum toxin mainly if associated with hyperhidrosis.…”