Aqueous extract of Paeoniae Radix Rubra prevents deep vein thrombosis by ameliorating inflammation through inhibiting GSK3β activity

Potential herb–drug interactions between anti-COVID-19 drugs and traditional Chinese medicine

“…Paeoniae Radix Rubra (Chishao in Chinese) is the dried root of Paeonia lactiflora Pall. and Paeonia veitchii Lynch 367 . Paeoniae Radix Rubra could be used for the treatment of patients with COVID-19 complicated with coagulation dysfunction via AKT serine/threonine kinase 1, TNF, vascular endothelial growth factor A, epidermal growth factor receptor, and mitogen-activated protein kinase 3 368 .…”

Application of UPLC-Q-TOF-MS with chemometric analysis and network pharmacology for comparison of different species: Paeonia lactiflora Pall. as an example

“…5 These compounds contribute to pharmacological activities, encompassing inflammation modulation, analgesia, spasmolysis, 6,7 liver protection, and antimicrobial and antiviral effects. [8][9][10] Although PRA and PRR were almost chemically similar, 11,12 variations in a growth environment, geographical origins, as well as different species resulted in distinct chemical compositions, content ratios, and clinical applications. 13 The current research on PRA and PRR has mainly focused on plant chemistry and pharmacological activities, with limited emphasis on their multicomponent components and categorical comparative studies.…”