Aqueous Suzuki coupling reaction catalyzed by water-soluble diimine/Pd(II) systems

Pd nanoparticles synthesized in situ with the use of Euphorbia granulate leaf extract: Catalytic properties of the resulting particles

“…In order to solve the problem, alternative environmentally benign processes for the Suzuki-Miyaura coupling reaction should be developed. There are some recent methods in the literature for Suzuki coupling reactions in water using soluble ligands and palladium homogeneous catalysts [13][14][15][16][17][18]. However, these methods suffer from certain disadvantages such as low TON (TON was only 20 when used up to 5.0 mol % of PdCl 2 ), high reaction temperature, long reaction times, tedious work-up, limited reusability of the expensive catalyst, which impacts cost, and palladium contamination in the product.…”

Palladium(II)NHC complexes containing benzimidazole ligand as a catalyst for CN bond formation

“…N-Heterocyclic carbenes (NHCs) are widely employed as supporting ligands in transition metal-catalyzed reactions, [1 -3] including ubiquitous palladium-catalyzed cross-coupling reactions, [4,5] in which their introduction has allowed a dramatic increase in catalytic performance. Furthermore, palladium complexes of the type Pd(pyridine)Cl 2 (NHC) and PdCl 2 (NHC) 2 have been found to exhibit potent anticancer activity.…”

Anchoring of palladium(II) in chemically modified mesoporous silica: An efficient heterogeneous catalyst for Suzuki cross-coupling reaction

“…Suzuki coupling of chlorobenzene with phenylboronic acid under both homogeneous and heterogeneous conditions over a variety of catalysts has been studied in the recent past (Table 2). Zhou et al have shown Suzuki coupling of chlorobenzene by water-soluble Pd(II)-diimine complex gives only 20% yield [32]. Further, [PdBr 2 {et(impy)} 2 ] complex of ligand yields no desired products in case of chlorobenzene [33].…”