Arcanobacterium haemolyticum bacteremia presenting as severe sepsis: A case report and review of the literature

Polymicrobial arcanobacterium haemolyticum intracerebral abscess: A case report and review of the literature

“…Anginosus were identified in this patient’s samples, given the burden of arcanobacterium in surgical and blood cultures, and the classic initial presentation, A. haemolyticum was thought to represent the primary pathogen. In line with this case, polymicrobial infection may occur in a significant minority of cases, as highlighted by a recent review of cases of A. haemolyticum, resulting in severe sepsis or complicated bacteraemia, which reports polymicrobial infection in 6 out of 20 cases [3] . In 5 of these cases, Fusobacterium necrophorum was also identified, as noted in the case presented.…”

“…While A. haemolyticum has been implicated predominantly in non-streptococcal pharyngitis and wound infections [9] , it has also been associated with severe sepsis and invasive disease including pulmonary abscesses, pleural empyemae, osteomyelitis, septic arthritis, spontaneous bacterial peritonitis and endocarditis [3] , [10] , [11] , [12] , [13] , [14] , [15] . A. haemolyticum is also associated with severe central nervous system infections; in one case series of patients with severe infection, CNS infections were present in 6 of 23 cases [9] .…”

“…Arcanobacterium haemolyticum is an uncommon organism classically associated with pharyngitis in immunocompetent adolescents and young adults [1] , [2] . In rare cases, A. haemolyticum may result in severe local or systemic disease [3] . A. haemolyticum may present alongside other organisms, including fusobacterium necrophorum, a respiratory commensal implicated in a minority of A. haemolyticum infections [3] .…”

“…In rare cases, A. haemolyticum may result in severe local or systemic disease [3] . A. haemolyticum may present alongside other organisms, including fusobacterium necrophorum, a respiratory commensal implicated in a minority of A. haemolyticum infections [3] . This article presents an illustrative case of a 21-year-old immunocompetent male with a polymicrobial A. haemolyticum intracerebral abscess following an upper respiratory tract infection and reviews the literature regarding A. haemolyticum intracerebral complications.…”

Double whammy: Delayed cerebral ischemia of a 19-year-old secondary to sinogenic complications from an uncommon bacterial sinusitis, Arcanobacterium haemolyticum

“…Arcanobacterium haemolyticum is a species of bacteria classified as a Gram-positive, facultatively anaerobic, beta-haemolytic, bacillus. First described in 1946, it was later reclassified from Corynebacterium to “Arcano-”, translating to “secretive” bacteria due to its previous resemblance [1] . Cultures of A haemolyticum can be found as normal skin flora and pharynx of healthy individuals and may often be overlooked as the causative agent of symptoms during an infection [2] .…”