Are there clinical signs and symptoms of infection to indicate the presence of multidrug-resistant bacteria in venous ulcers?

Santos, Silvana de Lima Vieira dos; Martins, Marlene Andrade; Prado, Marinésia Aparecida do; Soriano, José Verdú; Bachion, Maria Márcia

doi:10.1016/j.jvn.2017.08.001

Cited by 6 publications

(15 citation statements)

References 32 publications

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“…The search in the databases resulted in 507 studies; and, after sorting by title, abstract, and application of the inclusion and exclusion criteria, 43 articles were selected. Then, all of them were submitted to full and critical reading, culminating in the selection of 28 studies of which 16 (57.1%) were found in the Medline database (9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24) ; 6 (21.4%), in the BVS database (25)(26)(27)(28)(29)(30) , of which 66.7% (n = 4) in the LILACS database (26)(27)(28)30) and 33.3% (n = 2) in the IBECS databases (25,29) ; and 6 articles (21.4%) found at CINAHL (31)(32)(33)(34)(35)(36) .…”

Section: Resultsmentioning

confidence: 99%

“…As for the year of publication, 7.1% matched 2009 (9,25) ; 10.7%, 2010 (10)(11)31) ; 3.6%, 2012 (26) ; 3.6%, 2013 (12) ; 7.1%, 2014 (13,27) ; 10.7%, 2015 (14,(28)(29) ; 3.6%, 2016 (15) ; 25%, 2017 (16)(17)(18)(19)(20)30,32) ; 25% , 2018 (21)(22)(23)(24)(33)(34)(35) ; and 3.6%, 2019 (36) . Regarding the country of the study, 21.4% were done in India (12,15,18,(22)(23)(24) ; 21.4%, in Brazil (13,20,(26)(27)(28)30) ; 10.7%, in China (11,21,32) ; 7.1%, in Turkey (16,35) ; 10.7%, in Spain (25,29,36) ; and 7.1%, in Mexico (14,…”

Section: Resultsmentioning

confidence: 99%

“…Regarding the etiology of ulcers with infection, 78.6% were due to diabetes (10)(11)(12)(14)(15)(16)(17)(18)(19)(21)(22)(23)(24)(25)28,(30)(31)(32)(33)(34)(35)(36) ; 21.4%, venous (9,13,20,(26)(27)29) ; and 3.6%, arterial (29) . Regarding the location of the studies, 35.7% were outpatient (13,16,20,23,(26)(27)29,31,33,36) , and 64.2% occurred in hospital un its (9)(10)(11)(12)(14)(15)(17)(18)(19)(21)(22)(24)…”

Section: Resultsmentioning

confidence: 99%

“…Yildiz PA, Özdil T, Dizbay M, Tunçcan OG, Hizel K. Peripheral arterial disease increases the risk of multidrug-resistant bacteria and amputation in diabetic foot infections (35) 2018 Turkey The tests performed to identify microorganisms in hospitalized patients were biopsy (fragment of wound tissue) in 55.5% (9)(10)(11)(17)(18)(19)22,25,30,35) of cases, and swab also in 55.5% (9)(10)12,(14)(15)21,24,28,32,34) , while for those treated in outpatient clinics, the method that was most used was the swab (13,16,20,23,(26)(27)29,31,33,36) (Figure 2). Among the outpatient studies that performed swabbing, 30% (n = 3) mentioned its execution via the Levine technique (which consists of a technique with greater quantitative recovery of microorganisms).…”

Section: Descriptive N = 126 Culture and Antibiogrammentioning

confidence: 99%

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Microbiological profile of leg ulcer infections: review study

et al. 2021

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Objectives: to analyze the microbiological profile of leg ulcers of patients treated at outpatient clinics and hospitals regarding the type of microorganism, microbiological selection of antibiotics, and techniques for the collection of culture material. Methods: literature review performed on LILACS, IBECS, MEDLINE, and CINAHL databases, resulting in a descriptive analysis of 27 studies. Results: 35.7% of the studies occurred in an outpatient care scenario; and 64.2% in hospitals. There was a predominance of swab (100%) in outpatient care and biopsy (55.5%) in the hospital. Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus were more common at both levels of assistance. Methicillin-resistant Staphylococcus aureus was isolated in both. Conclusions: the microbiological profile of infections was similar, with the presence of resistant bacteria in both environments. This fact causes concern and raises the need for research to elucidate it. The studies did not compare the effectiveness between biopsy and swab.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Descriptive N = 126 Culture and Antibiogrammentioning

confidence: 99%

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Microbiological profile of leg ulcer infections: review study

et al. 2021

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“…Se han reportado estudios en los que se realizan cultivos de secreciones en úlceras con diagnóstico clínico de sobreinfección (9-13), sin embargo, el origen polimicrobiano de este tipo de infecciones y la baja sensibilidad y especificidad halladas en los cultivos de secreciones, han hecho que surja la necesidad de realizar estudios microbiológicos más específicos (14)(15)(16)(17). Cada vez es más claro que no todos los pacientes se benefician de los mismos dada la alta tasa de falsos positivos y baja correlación clínica (18)(19)(20)(21)(22), por lo que actualmente se indican estos estudios en poblaciones especiales con algún grado de inmunocompromiso (23)(24)(25)(26)(27)(28).…”

Section: Introductionunclassified

Caracterización epidemiológica y microbiológica, mediante cultivo de biopsia, de los casos de úlceras venosas sobreinfectadas en el Hospital Universitario del Caribe.

Bretón¹,

Barakat²,

Cano

2020

Rev Cienc Biomed

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Introducción: las úlceras venosas son una manifestación de insuficiencia venosa severa, con capacidad para deteriorar la calidad de vida. La sobreinfección es una complicación frecuente y genera altos costos al sistema de salud, estancias hospitalarias prolongadas y otras complicaciones, incluyendo el aumento de la resistencia microbiana debido a que no se ha establecido cuál es el estudio ideal para identificar el germen causal, y por ende, son procesos manejados con esquemas empíricos.Objetivo: caracterizar epidemiológica y microbiológicamente, mediante cultivo de biopsia, los casos de úlceras venosas sobreinfectadas en el Hospital Universitario del Caribe (H.U.C.).Métodos: diseño descriptivo, corte transversal, prospectivo. Se tomaron pacientes mayores de 18 años los cuales presentaban úlceras venosas sobreinfectadas y hospitalizados en el H.U.C. Se obtuvo mediante encuesta información sociodemográfica, clínica y paraclínicos; con toma de muestras por biopsia para estudio microbiológico. Se realizó análisis univariado y bivariado.Resultados: se obtuvieron 53 pacientes, 29 hombres (54.7%) y 24 mujeres (45.3%), con promedio de 60,5 ± 14,6 años. Hubo una prevalencia de hipertensión en 35 pacientes (66%), diabetes mellitus 26 (49.1%), tabaquismo 17 (32.1%) y enolismo 14 (26.4%). Los síntomas más frecuentes fueron eritema (83.0%), dolor (79.2%) y edema (79.2%). En 56.6% de los casos se aisló Staphylococcus aureus aunque fueron frecuentes los resultados polimicrobianos.Conclusiones: la prevalencia de úlceras venosas es mayor en el sexo masculino, en las cuales, el microorganismo más frecuentemente aislado es S. aureus, aunque se obtuvieron perfiles polimicrobianos. Deben realizarse más estudios para un mayor conocimiento de las características sociodemográficas y microbiológicas de estos pacientes.

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Microbiological Status of Venous Leg Ulcers and Its Predictors: A Single-Center Cross-Sectional Study

Cwajda‐Białasik

Mościcka

Jawień

et al. 2021

IJERPH

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Venous leg ulcers are frequently colonized by microbes. This can be particularly devastating if the ulcer is infected with alert pathogens, i.e., highly virulent microorganisms with well-developed mechanisms of antibiotic resistance. We analyzed the microbiological status of venous leg ulcers and identified the clinicodemographic predictors of culture-positive ulcers, especially in ulcers with colonization by alert pathogens. Methods: This study included 754 patients with chronic venous leg ulcers. Material for microbiological analysis was collected by swabbing only from patients who did not receive any antibiotic treatment. Results: A total of 636 (84.3%) patients presented with culture-positive ulcers. Alert pathogens, primarily Pseudomonas aeruginosa, were detected in 28.6% of the positive cultures. In a logistic regression model, culture-positive ulcers were predicted independently by age > 65 years, current ulcer duration > 12 months, and ulceration area greater than 8.25 cm2. Two of these factors, duration of current ulcer > 12 months and ulceration area > 8.25 cm2, were also identified as the independent predictors of colonization by alert pathogens. Conclusions: Colonization/infection is particularly likely in older persons with chronic and/or large ulcers. Concomitant atherosclerosis was an independent predictor of culture-negative ulcers.

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Are there clinical signs and symptoms of infection to indicate the presence of multidrug-resistant bacteria in venous ulcers?

Cited by 6 publications

References 32 publications

Microbiological profile of leg ulcer infections: review study

Microbiological profile of leg ulcer infections: review study

Caracterización epidemiológica y microbiológica, mediante cultivo de biopsia, de los casos de úlceras venosas sobreinfectadas en el Hospital Universitario del Caribe.

Microbiological Status of Venous Leg Ulcers and Its Predictors: A Single-Center Cross-Sectional Study

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