ARFI: from basic principles to clinical applications in diffuse chronic disease—a review

Bruno, Costanza; Minniti, Salvatore; Bucci, A.; Mucelli, Roberto Pozzi

doi:10.1007/s13244-016-0514-5

Cited by 71 publications

(68 citation statements)

References 85 publications

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“…In our ROC analyses, AUCs of VTQ for LF in the CHB cohort and the CHC cohort ranged from 0.75 to 0.90 and 0.78 to 0.88, respectively. Virtual touch quantification had strong P ‐values for predicting the severity of LF in most of the multivariate analyses, which were in line with previous reports . A recent study compared three elastographic methods, transient elastography, 2‐D shear wave elastography, and ARFI‐VTQ, in CLD patients and no notable differences in diagnostic accuracy were observed among them for the severity of LF .…”

Section: Discussionsupporting

confidence: 88%

“…Several meta‐analyses and systematic reviews confirmed clinical utility of ARFI for the evaluation of the severity of LF . Usefulness of ARFI elastography is reported in not only CLDs but also chronic kidney diseases . Acoustic radiation force impulse is a reliable and reproducible assessment method with favorable intra‐ and interobserver levels of agreement, although there are some limitations .…”

Section: Introductionmentioning

confidence: 99%

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Liver fibrosis markers as assessed by ultrasound elastography and serum samples: A large comparative study in hepatitis virus B and C liver diseases

Nishimura

Iijima

Nishikawa

et al. 2019

Hepatology Research

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Aim We aimed to compare the well‐established liver fibrosis (LF) markers in Japanese patients with chronic hepatitis B (CHB, n = 331) and chronic hepatitis C (CHC, n = 886) and to discuss possible causes of differences in results between CHB patients and CHC patients. Methods Virtual touch quantification (VTQ) in acoustic radiation force impulse, Fibrosis‐4 (Fib‐4) index, aspartate aminotransferase to platelet ratio index (APRI), and hyaluronic acid (HA) were compared between the two cohorts. As an additional investigation, total collagen proportional area (TCPA, %) was tested using liver pathological samples (n = 83). Results Significant LF (F2 or greater) and advanced LF (F3 or greater) were identified in 153 (46.2%) and 76 (23.0%) patients in the CHB cohort and 579 (65.3%) and 396 (44.7%) patients in the CHC cohort. The median VTQ, Fib‐4 index, APRI, and HA values in the CHB cohort were 1.20 m/s, 1.36, 0.44, and 25 ng/mL; those in the CHC cohort were 1.32 m/s, 2.60, 0.74, and 65.5 ng/mL (P‐values, all <0.0001). Similar tendencies were noted by F stage‐based stratification. The median TCPA in the CHB cohort and the CHC cohort were 8.5% and 12.7% (P < 0.0006). The TCPA values in the CHC cohort were higher than those in the CHB cohort regardless of LF stage. Conclusion Values of LF markers in CHB patients can differ from those in CHC patients even in the same LF stage. Difference in total amount of collagen fiber in CHB and CHC appears to be linked to the difference.

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Section: Discussionsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Liver fibrosis markers as assessed by ultrasound elastography and serum samples: A large comparative study in hepatitis virus B and C liver diseases

Nishimura

Iijima

Nishikawa

et al. 2019

Hepatology Research

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“…The SWV cannot be measured in tissue deeper than 8 cm from the skin; therefore, the value of SWV measurement in superficial tissues may differ from that in deeper ones. 34,36 Fortunately, we were able to measure the SWV at a depth of 3 to 6 cm from the skin in this study.…”

Section: Discussionmentioning

confidence: 93%

Multiparametric Quantitative Ultrasound Imaging in Assessment of Chronic Kidney Disease

Gao

Perlman

Kalache

et al. 2017

J of Ultrasound Medicine

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Purpose To evaluate the value of multiparametric quantitative ultrasound imaging (QUI) in assessing chronic kidney disease (CKD) using kidney biopsy pathology as the reference standard. Methods We prospectively measured multiparametric QUI markers with grayscale, spectral Doppler, and acoustic radiation force impulse imaging in 25 patients with CKD prior to their kidney biopsies and in 10 healthy volunteers. Based on all pathology (glomerulosclerosis, IF/TA, arteriosclerosis, and edema) scores, the 25 CKD patients were classified into mild (no grade 3 and < 2 of grade 2) and moderate to severe (at least 2 of grade 2 or 1 of grade 3) CKD groups. Multiparametric QUI in the study included kidney length, cortical thickness, pixel-intensity, parenchymal shear wave velocity (SWV), intrarenal artery peak systolic velocity (PSV), end diastolic velocity (EDV), and resistive index (RI). We tested the difference in QUI parameters among mild CKD, moderate to severe CKD, and healthy controls using ANOVA, analyzed correlations of QUI parameters to kidney pathology scores and to eGFR using the Pearson correlation coefficient, and examined the diagnostic performance of QUI parameters in determining moderate CKD and eGFR <60 using ROC curve analysis. Results There were significant differences in cortical thickness, pixel-intensity, PSV, and EDV among the 3 groups (all p< 0.01). Among QUI parameters, the top AUROCs of PSV and EDV for determining pathologic moderate to severe CKD were 0.88 and 0.97, and for eGFR <60 were 0.76 and 0.86, respectively. Moderate to good correlations were found for PSV, EDV, and pixel-intensity to pathology score and eGFR. Conclusion PSV, EDV, and pixel-intensity are valuable in determining moderate to severe CKD. The value of SWV in assessing CKD needs further investigation.

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“… elastography point shear wave for pancreatitis 1 большое количество исследований, указывающих на возможность использования эластометрии при характеристике поражений различных органов [2,9,12,13,16,24,28,31,46,48,54,71,79,80]. Как известно, эластография -это метод неинвазивного исследования жесткости тканей путем анализа эластической деформации [16,77].…”

Section: свободные терминыunclassified

“…На сегодняшний день это пока единственная опубликованная работа по данному направлению, обнаруженная нами [3]. Несмотря на то, что большинство исследований выполнено одинаковой технологией использования акустического импульса, единого мнения о нормальных характеристиках жесткости паренхимы поджелудочной железы пока не существует [13,30,41,75,76]. Различия в показателях, по мнению авторов, можно объяснить сразу несколькими причинами [13,30,75,76].…”

Section: свободные терминыunclassified

Ultrasound Elastography for Assessing Acute Pancreatitis

Kabanenko¹,

Khomutova²,

Ignatiev³

2019

Rejr

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стрый панкреатит -это острое воспаление поджелудочной железы. Пациенты с тяжелым острым панкреатитом более склонны к развитию осложнений и имеют гораздо более высокий уровень смертности. По мнению многих авторов, результат исхода острого панкреатита определяется двумя факторами: объемом деструкции (некроза) и нарушением функции органа. Степень выраженности этих факторов влияет на развитие тяжелых осложнений при остром панкреатите. Основной целью новых разработок в области ультразвуковой визуализации является увеличение диагностических критериев раннего выявления этих осложнений. Эластография одна из новых разработок в области такой визуализации, позволяющая характеризовать жесткость ткани. В статье проанализированы научные публикации, рассматривающие качественные и количественные критерии анализа эластограмм, позволяющих оценить жесткость паренхимы поджелудочной железы, проведен анализ публикаций, повествующих о возможностях использования ультразвуковой эластографии в диагностике острого панкреатита.Ключевые слова: эластография, точечная эластография сдвиговой волной (SWE point shear wave elastography, AFRI) ,поджелудочная железа, острый панкреатит.Контактный автор: Кабаненко Т.П., cute pancreatitis is an acute inflammation of the pancreas. The patients who have severe acute pancreatitis are more likely to develop complications and have a much higher mortality rate. According to many authors, the outcome of acute pancreatitis is determined by two factors: the volume of destruction (necrosis) and the violation(break) of organ function. The severity of these factors affects the development of severe complications in acute pancreatitis. The main goal of new developments in ultrasound imaging is to increase the diagnostic criteria for early detection of these complications. Elastography is one of the new developments in ultrasound imaging, which allows characterizing the stiffness of the tissue. The paper represents generalization the results of an analysis of scientific publications examining the qualitative and quantitative criteria for analyzing elastograms that allow one to evaluate the stiffness of the pancreatic parenchyma. Also, the analysis of the publications telling about possibilities of use of ultrasonic elastography in diagnostics of an acute pancreatitis has been conducted

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ARFI: from basic principles to clinical applications in diffuse chronic disease—a review

Cited by 71 publications

References 85 publications

Liver fibrosis markers as assessed by ultrasound elastography and serum samples: A large comparative study in hepatitis virus B and C liver diseases

Liver fibrosis markers as assessed by ultrasound elastography and serum samples: A large comparative study in hepatitis virus B and C liver diseases

Multiparametric Quantitative Ultrasound Imaging in Assessment of Chronic Kidney Disease

Ultrasound Elastography for Assessing Acute Pancreatitis

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