Stroke is defined by the WHO as a rapid deterioration in neurological symptoms lasting more than 24 hours with a vascular origin (1). It is an important cause of longterm morbidity and mortality in children. The incidence of childhood stroke varies amongst different population studies and lies between 2-13 per 100,000 (2-4).Paediatric stroke is classified as either perinatal (≤28 days of age) or childhood (>28 days of age) (5). The focus of this article will be on childhood stroke.Childhood stroke can be further subdivided into ischaemic and haemorrhagic stroke (Figure 1). Ischaemic stroke encompasses both arterial ischaemic stroke (AIS) and venous infarction secondary to cerebral venous sinus thrombosis (CVST) or cortical vein thrombosis (6). CVST is frequently accompanied by areas of parenchymal haemorrhage.
AIS
Epidemiology and risk factorsPaediatric stroke is classified as either perinatal/neonatal (28 days of age) or childhood (>28 days of age). The definition of AIS is shown in Table 1.The major risk factors that cause adult strokes such as atherosclerosis and associated conditions such as hypertension and dyslipidaemia are irrelevant in childhood. The aetiology of AIS in childhood differs from adults, is complex and more often multifactorial. The age of the child is also an important factor with stroke in the neonatal stage having a unique set of considerations to strokes in an older Review Article on Pediatric Neuroradiology for Trainees and Fellows: An Updated Practical Guide