Arterial Oxygen Tension in Relation to Age in Healthy Subjects

Sorbini, C. A.; Grassi, Vittorio; Solinas, E; Muiesan, G; Cheney, Frederick W.

doi:10.1097/00132586-196910000-00005

Cited by 26 publications

(33 citation statements)

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“…Arterial oxygen tension values were higher (mean 11-7 kPa) than those given by Ulmer and Reichel (1963) and Sorbini et al (1968) for healthy adults of the same age (mean 10-8 kPa), while arterial carbon dioxide tension values were normal. When arterial oxygen saturation was calculated using the data provided by the electrodes in the three patients whose arterial saturation was measured after discharge with a haemoreflector, it was seen that 20 years later oxygen saturation was higher.…”

Section: Resultsmentioning

confidence: 56%

Pulmonary gas transfer 20 years after pneumonectomy for pulmonary tuberculosis.

Gimeno¹,

Kraan²,

Orie³

et al. 1977

Thorax

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Orie, N. G. M., and Peset, R. (1977). Thorax, 32,[80][81][82][83] Pulmonary gas transfer 20 years after pneumonectomy for pulmonary tuberculosis. The changes in pulmonary function after pneumonectomy in 13 patients with pulmonary tuberculosis have been studied. The data at the time of two follow-up studies are compared with those obtained before the pneumonectomy. The first follow-up was carried out between 5 and 30 months postoperatively and the second between 20 and 24 years later. The results of this second follow-up show a relatively normal arterial oxygen saturation and gas transfer factor but an increased residual volume which cannot be explained by increasing age alone.

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Section: Resultsmentioning

confidence: 56%

Pulmonary gas transfer 20 years after pneumonectomy for pulmonary tuberculosis.

Gimeno¹,

Kraan²,

Orie³

et al. 1977

Thorax

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“…is mean +:1 SD for Pao2 in healthy subjects (Sorbini et al, 1968). In the sitting position four of 10 patients with ascites showed hypoxaemia and three of them had Pao2 values below 66 mmHg.…”

Section: Resultsmentioning

confidence: 99%

Hypoxaemia and cirrhosis of the liver.

Funahashi¹,

Kutty²,

Prater³

1976

Thorax

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. (1976). Thorax, 31,[303][304][305][306][307][308] Hypoxaemia and cirrhosis of the liver. In order to determine the frequency of hypoxaemia and to evaluate the role of increased closing capacity in producing hypoxaemia in patients with cirrhosis of the liver, 13 patients with well-established cirrhosis were studied. 'Arterial blood gases, spirometry, lung volume, and closing capacity measurements were made with the patients in the seated and recumbent positions after exclusion of cardiopulmonary dysfunction. Four of 13 and six of 12 patients exhibited significant hypoxaemia in the seated and recumbent positions respectively. Five of 13 patients showed a closing capacity greater than predicted. This frequency of increased closing capacity was not higher than in a group of smokers of the same age. Unlike Ruff et al. (1971), we did not find a consistent relationship between hypoxaemia and closing capacity.

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“…Young asthmatics tend to have a faster heart rate during exacerbations of asthma compared with older patients (Cooke, Crompton and Grant, 1979). In normal people, with advancing age, reduction in static lung volumes and decrease in gas transfer (Muiesan, Sorbini and Grassi, 1971) with increase in ventilation-perfusion inequality (Holland et al, 1968) and closing volume (Leblanc, Ruff and Milic-Emili, 1970) combine to produce hypoxaemia (Sorbini et al, 1968). Cardiovascular responses to hypoxaemia also diminish with age (Kronenberg and Drage, 1973) and this may explain why heart rate and pulsus paradoxus are less helpful signs in asthma in the elderly.…”

Section: Discussionmentioning

confidence: 99%

Assessment and management of acute asthma in the elderly: a comparison with younger asthmatics

Petheram

Jones

Collins

1982

Postgraduate Medical Journal

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Assessment on admission and responses to treatment were studied in 20 patients aged 65 years or over admitted with severe acute exacerbations of asthma and were compared with patients aged 40 years or less who were managed similarly. The elderly asthmatic had less marked tachycardia and pulsus paradoxus compared to the younger group for similar degrees of airways obstruction and arterial blood gas abnormalities. Assessment confined to physical examination would, therefore, have underestimated the severity of their asthma. The rates of improvement in airflow obstruction were similar in both young and old but those elderly patients who had required maintenance oral corticosteroids were less likely to reach their predicted peak expiratory flow rate (PEFR) than their peers or younger patients.

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Arterial Oxygen Tension in Relation to Age in Healthy Subjects

Cited by 26 publications

References 0 publications

Pulmonary gas transfer 20 years after pneumonectomy for pulmonary tuberculosis.

Pulmonary gas transfer 20 years after pneumonectomy for pulmonary tuberculosis.

Hypoxaemia and cirrhosis of the liver.

Assessment and management of acute asthma in the elderly: a comparison with younger asthmatics

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