Arterial stiffness during pregnancy and after delivery

Рябоконь, Н. Р.; Кузнецова, Л. В.; Зазерская, И. Е.; Казанцева, Т. И.; Шелепова, Е. С.; Яковлева, Н. Ю.

doi:10.18705/1607-419x-2015-21-6-614-622

Cited by 3 publications

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“…Встает вопрос о поисках методов доклинической диагностики данных осложнений. В последнее время для оценки степени адаптации сердечно-сосудистой системы к беременности используют показатели эластичности сосудов, к которым относятся скорость распространения пульсовой волны (СРПВ), индекс аугментации, модуль упругости [3][4][5][6]. Параметры центральной пульсовой волны (индекс аугментации) и СРПВ варьируют на протяжении физиологической беременности, средние значения которых свидетельствуют в пользу высокой эластичности сосудов.…”

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Features of vascular stiffness in pregnancy complicated by preeclampsia and postpartum

et al. 2016

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Actuality. Pre-eclampsia during pregnancy is a major cause of maternal mortality, intra- and neonatal pathology [1]. Sharply there is a question about the search method of determining the predictors of pre-eclampsia and the degree of influence on a woman’s body for the purpose of timely diagnosis and treatment. Interest in the method of determining the parameters of arterial stiffness is growing every year because of the availability and relative ease of use to determine the degree of maladjustment of the vascular system and assessing the risks of cardiovascular disease.Objective. Evaluation of indicators characterizing stiffness of the arterial wall in pre-eclampsia during pregnancy and after childbirth.Materials and Methods. In a prospective cohort comparative study included 62 pregnant women aged 19 to 35: 35 women with physiological pregnancy without physical abnormalities and 27 women with preeclampsia moderate, without preeclampsia history. Surveys were carried out in time for 22-24, 32-34 weeks of gestation and at 8 hours after delivery. To evaluate the rigidity of the vascular wall used complex BPLab.Results. In pregnant women with pre-eclampsia there is an increase of arterial stiffness parameters at 22 weeks of pregnancy in comparison with the original data at 12 weeks of gestation, IA uvelichilsyana 29.3%, 12.5% PWV. Most significantly in the intervention group to the third trimester have changed the following parameters: IA averaged – - 28% (± 5,5) + 37% from baseline, PWV – 8 m/s (± 0,9) + 12,5%, in the control group: IA – - 39,6% (± 8,1) + 12,2% in comparison with the data of 12 weeks’ gestation, PWV – 7.43 m/s (± 0,82) + 12,5%, demonstrating various adaptive features of the vascular wall in groups. In the early postpartum period significantly positive dynamics of arterial stiffness parameters in the group with physiological pregnancy, pre-eclampsia in the group with the values remain the same or change slightly. Conclusions. Thus, from the data of the pulse wave analysis is the best method for measuring vascular stiffness non-invasively in pregnant women. This method demonstrates the physiological adaptation of vessels to the gestational process, and shows the changes associated with preeclampsia as the background of pregnancy and after childbirth. Thus, this method makes it possible to evaluate the adaptive reserve of the vascular wall for the purpose of forecasting the development of cardiovascular complications.

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Section: Introductionunclassified

Features of vascular stiffness in pregnancy complicated by preeclampsia and postpartum

et al. 2016

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The characteristics of vascular elastic properties and the immune inflammatory response in pregnant women with hypertension

Panova¹,

Kudryashova²,

Rokotyanskaya³

et al. 2019

Ross. vestn. akush.-ginekol.

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Current views on the assessment of vascular wall elasticity in pregnant women with arterial hypertension

Krasilnikova

Borovkova

2022

jour

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Introduction. Arterial hypertension is the most common somatic pathology in pregnant women. Arterial hypertension is a factor of high risk for the development of severe preeclampsia, placental insufficiency, intrauterine growth restriction, premature birth, maternal and perinatal mortality, nervous disorder and vascular heart disease of newborns and women’s distant cardiovascular disorders. The pathogenesis of gestational complications is associated with pathology of placentation, endothelial dysfunction and a decrease in vascular elasticity. The pathogenesis has not studied yet. Nowadays there are no tests with enough sensitivity and specificity ensuring early diagnostics and risk identification at development of great obstetric syndromes. Aim of the study was to improve our understanding about a clinical and prognostic role of vascular wall elasticity in pregnant women with arterial hypertension. Materials and Methods. We searched publications and analyzed literature using various scientific databases, including Index Medicus, PubMed/MEDLINE, Embase, Cochrane Library and Russian scholarly journals related to obstetrics, gynecology, cardiology for the last 9 years. Results and Discussion. Today changes in the elastic properties of arteries is a modern marker of a high risk of cardiovascular events in patients with essentialhypertension. Endothelial dysfunction develops already in the early stages of arterial hypertension and initiates structural changes in the vascular wall and an increase in arterial stiffness. High activity of the sympathetic nervous system is the cause of changes in the elastic properties of arteries in pregnant women with arterial hypertension. Conclusion. The role of vascular wall elasticity in pregnant women with arterial hypertension is of tremendous importance and deserves close attention. The study of elastic properties of vessels is relevant for assessing the risk of gestational complications in pregnant women with arterial hypertension.

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Arterial stiffness during pregnancy and after delivery

Cited by 3 publications

References 0 publications

Features of vascular stiffness in pregnancy complicated by preeclampsia and postpartum

Features of vascular stiffness in pregnancy complicated by preeclampsia and postpartum

The characteristics of vascular elastic properties and the immune inflammatory response in pregnant women with hypertension

Current views on the assessment of vascular wall elasticity in pregnant women with arterial hypertension

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