Artérite à cellules géantes et maladie de Takayasu : aspects épidémiologiques, diagnostiques et thérapeutiques

Chaigne-Delalande, Séverin; Menthon, Mathilde de; Lazaro, Estibaliz; Mahr, Alfred

doi:10.1016/j.lpm.2012.07.011

Cited by 6 publications

(1 citation statement)

References 91 publications

(94 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…GCA is a granulomatous vasculitis of unknown origin and targets large vessels with predominance for the aortic arch and the cranial branches [1, 2, 6]. Most patients in GCA present cranial manifestations described above; thus, GCA was previously called temporal arteritis.…”

Section: Discussionmentioning

confidence: 99%

Giant cell arteritis without cranial manifestations caused mesenteric involvement: a case report

et al. 2019

View full text Add to dashboard Cite

Background Giant cell arteritis (GCA) is a granulomatous vasculitis and targets large vessels with predominance for the aortic arch and the cranial branches. GCA with cranial symptoms shows headache, jaw claudication, and ophthalmologic symptoms and thus was previously called temporal arteritis. Recently, cases of GCA without cranial manifestations and extracranial GCA have been reported. Case presentation A 76-year-old woman was referred to our hospital complaining of sudden abdominal pain and high fever. Her present history of illness did not show any cranial symptoms such as headache, visual disturbance, or stroke. CT images showed severe thickening of the small intestinal mesentery and massive ascites. She was diagnosed to have acute abdomen probably with gastrointestinal perforation and underwent the emergent laparotomy. Excisions of a 60-cm length of the jejunum including the thickening mesenteric lesion were carried out. Marked hypertrophy of the vascular intima and mild stenosis of the arterial lumen were displayed with infiltration of lymphocytes, neutrophils, and eosinophils. Scattered multinucleated giant cells on the endothelium, in the intima, media, and adventitia were demonstrated. Elastica van Gieson stain showed focal loss and fragmentation of the internal elastic lamina. Histopathological examinations showed typical GCA. Her postoperative process was uneventful without any symptoms, and she was followed as an out-patient prescribed with daily doses of 40 mg of prednisolone. Conclusions We hereby report a rare case of mesenteric involvement in GCA without cranial manifestations and elucidate the histopathological features of extracranial GCA in arteries as well as veins and jejunum.

show abstract

Section: Discussionmentioning

confidence: 99%