Arthropathy of haemochromatosis. Clinical and radiological analysis of 63 patients with iron overload.

Destructive arthropathy in chondrocalcinosis articularis.

“…Progressive FIG. 4 (Hamilton, Williams, Barlow, and Smith, 1968;Dymock, Hamilton, Laws, and Williams, 1970). Shoulder radiographs similar to that seen in the second patient (Fig.…”

Osteoarticular changes and synovial biopsy findings in Wilson's disease.

“…Chondrocalcinosis of the kneejoints was not found in our patients, but its presence has been reported and suggests a similarity with the arthropathy of other metabolic diseases (Schumacher, 1964;Boudin and others, 1964;Dymock, Hamilton, Laws, and Williams, 1970;Bywaters, Dorling, and Sutor, 1970). Rickets or osteomalacia have been described as an unusual finding in Wilson's disease (Finby and Bearn, 1958;Mehta and Shinde, 1965;Cavallino and Grossman, 1968) to which nutritional factors may have contributed (Feller and Schumacher, 1972) There was no relationship between synovial membrane findings and radiographic changes.…”

Metacarpophalangeal arthropathy associated with manual labor (missouri metacarpal syndrome). clinical, radiographic, and pathologic characteristics of an unusual degenerative process

“…Antibodies to type JI collagen were not present. The ESR was elevated slightly in patient 4, but was normal in the remaining 6 patients. Most patients were tested repeatedly for RF, and 6 of 7 patients had positive results at least once; 2 patients had positive results the first time the test was performed, and 4 patients were RF-positive at the most recent determination.…”

“…These findings, which were usually bilateral, included diminished range of motion in the DIP joints (7 patients), PIE' joints (7 patients), wrists (6 patients), glenohumeral joints (3 patients), cervical spine (2 patients), and elbows (2 patients). Heberden's nodes and Bouchard's nodes were present in 7 and 6 patients, repsectively.…”

“…Clinicians evaluating severe osteoarthritic changes in the MCP joints tend to consider diagnoses of secondary osteoarthritis (OA) resulting from hemochromatosis (3)(4)(5)(6)(7)(8) or calcium pyrophosphate dihydrate (CPPD) crystal deposition (9)(10)(11)(12)(13). Both disorders are associated with bilateral degenerative arthropathy usually involving the second and third MCP joints, with loss of articular space, sclerosis, and cyst formation (3-15).…”