In order to investigate possible changes in the nucleo-cytoplasmic ratio of the muscle fibres during ageing, samples of quadriceps femoris from 15 normal individuals whose age ranged from 17 to 82 years were studied (autopsy material). The mean lesser diameter and the number and size of the muscle fibre nuclei were calculated using a planimetric technique. It was found that nucleo-cytoplasmic ratio increased significantly after the age of 60 years. This was due to a decrease in the mean fibre size whilst the number and the size of myonuclei remained unchanged. The resemblance of this finding to denervation atrophy changes is noted.

No abstract

A female aged 24 years, without any previous personal and family history of migraine, presented with migrainous attacks characterized by headache, dizziness and nausea, accompanied by sensory, motor, visual and aphasic disturbances. The duration of the attacks ranged from 10-30 minutes, except for one episode which was accompanied by confusion and excitation and which lasted for many hours. The attacks recurred for approximately 6 weeks during which the condition of the patient was excellent between attacks. The patient recovered completely and in two years of follow-up has not had any further migrainous attacks. The C.S.F. showed a predominantly lymphocytic pleocytosis and increased protein. A "symptomatic" migraine condition stemming from an inflammatory reaction of the meninges is thus suggested.

No abstract

No abstract