Purpose Press-it ixation is a hardware-free technique in anterior cruciate ligament reconstruction (ACLR). The purpose of this review was to quantitatively assess the risk proile and outcomes of press-it ixation and provide an update on its efectiveness compared to more standard ixation techniques of ACLR. Methods The electronic databases PUBMED, MEDLINE, and EMBASE were searched on March 26, 2020 for therapeutic randomized controlled trials (RCT) addressing press-it ixation for primary ACLR. The Grading of Recommendations Assessment, Development and Evaluation tool was used to assess the quality for randomized studies. A meta-analysis with a random-efects model was used to pool applicable outcomes data. Results A total of six eligible RCTs were included in this review. There were 292 patients (72.9% male) with a mean age of 28.8 ± 3.8 years and a mean follow-up of 81.3 ± 88.3 months that underwent press-it ACLR on the femoral, tibial or both tunnels. Femoral ixation techniques included press-it ixation (96.6%) and cross-pin ixation (3.4%). Tibial ixation techniques included press-it (37.0%), staples (28.1%), interference screws (21.2%) and abarticular post-screws (13.7%). Graft options included bone-patellar tend--bone autografts (73.6%) and semitendinosus and gracilis tendon autograft (26.4%). Signiicant improvements (p < 0.05) from baseline to follow-up were found for clinical outcomes. Signiicantly less postoperative bone tunnel enlargement (p < 0.05) was found with tibial press-it ixation when compared to biodegradable screws. The overall complication rate was 13.3%. There were no signiicant diferences in complication rates [odds ratio = 0.84 (95%CI 0.43-1.66); p = n.s.] (I 2 = 0%) between patients undergoing femoral press-it ixation and femoral metal interference screw ixation.
ConclusionThe overall graft failure and revision rates with press-it ACLR were low. There were no signiicant diferences in complication rates between patients undergoing femoral press-it and femoral metal interference screw ixation. Included studies found that patients undergoing press-it ixation for ACLR had signiicant improvements in functional outcome scores postoperatively and had signiicantly reduced postoperative bone tunnel enlargement compared to patients undergoing bioabsorbable ixation. Thus, early evidence suggests that press-it ixation appears to be a good option for patients undergoing ACLR. Level of evidence I.