Arthroscopic ACL reconstruction using patellar bone tendon autograft and Rigidfix fixation - A midterm functional outcome

Sudevan, Prasanth Jayakumari; Chandrasekharan, Jayadev; Sambandam, Senthil; Rohinikumar, Ganeshkumar Jayasree; Annamalai, Sakthivel; Mounasamy, Varatharaj

doi:10.11138/mltj/2017.7.2.247

Cited by 2 publications

References 30 publications

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Tunnel Widening of Acl Reconstruction Augmented by an Platelet Rich Osteoconductive-Osteoinductive Allograft Compound: A Randomized Blind-Analysis Pilot Study

Solomon

Hommen

Travascio

2022

Preprint

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Background: The anterior cruciate ligament (ACL) is a commonly injured ligament in the knee. Bone tunnel widening is a known phenomenon after soft-tissue ACL reconstruction and etiology and clinical relevance have not been fully elucidated. Osteoconductive compounds are biomaterials providing an appropriate scaffold for bone formation such as demineralized bone matrix. Osteoinductive materials contain growth factors stimulating bone lineage cells and bone growth. A possible application of osteoinductive/osteoconductive (OIC) material is in ACL surgery. Questions/Purposes: We hypothesized that OIC placed in ACL bone tunnels: 1) reduces tunnel widening, 2) improves graft maturation and 3) reduces tunnel ganglion cyst formation. To test this hypothesis, this study evaluated the osteogenic effects of demineralized bone matrix (DBM) and platelet rich plasma (PRP) on tunnel widening, graft maturation, and ganglion cyst formation. Study Design: Randomized controlled clinical trial pilot study. Methods: A total of 26 patients electing ACL reconstruction surgery were randomized between OIC and control group. Measurements of tunnel expansion and graft-tunnel incorporation were conducted via quantitative image analysis of MRI scans performed at six months after surgery for both groups. Results: No patients had adverse post-operative reactions or infections. The use of OIC significantly reduced tunnel widening (p < 0.05) and improved graft maturation (p < 0.05). Patients treated with OIC presented with a significantly lower prevalence of ganglion cyst compared to the control group (p < 0.05). Conclusion: The use of OIC has measurable effects on the reduction of tunnel widening, improved graft maturation and decreased size of ganglion cyst after ACL reconstruction. Clinical Relevance: This study explored the utilization of biologics to minimize bone tunnel widening in ACL reconstruction surgery. Study Design: Randomized controlled clinical trial.

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Tunnel Widening of Acl Reconstruction Augmented by an Platelet Rich Osteoconductive-Osteoinductive Allograft Compound: A Randomized Blind-Analysis Pilot Study

Solomon

Hommen

Travascio

2022

Preprint

View full text Add to dashboard Cite

show abstract

Effects of Platelet-Rich Osteoconductive–Osteoinductive Allograft Compound on Tunnel Widening of ACL Reconstruction: A Randomized Blind Analysis Study

2022

View full text Add to dashboard Cite

The anterior cruciate ligament (ACL) is a commonly injured ligament in the knee. Bone tunnel widening is a known phenomenon after soft-tissue ACL reconstruction and etiology and the clinical relevance has not been fully elucidated. Osteoconductive compounds are biomaterials providing an appropriate scaffold for bone formation such as a demineralized bone matrix. Osteoinductive materials contain growth factors stimulating bone lineage cells and bone growth. A possible application of osteoinductive/osteoconductive (OIC) material is in ACL surgery. We hypothesized that OIC placed in ACL bone tunnels: (1) reduces tunnel widening, (2) improves graft maturation, and (3) reduces tunnel ganglion cyst formation. To test this hypothesis, this study evaluated the osteogenic effects of demineralized bone matrix (DBM) and platelet-rich plasma (PRP) on tunnel widening, graft maturation, and ganglion cyst formation. This was a randomized controlled clinical trial pilot study. A total of 26 patients that elected to have ACL reconstruction surgery were randomized between the OIC and control group. Measurements of tunnel expansion and graft-tunnel incorporation were conducted via the quantitative image analysis of MRI scans performed at six months after surgery for both groups. No patients had adverse post-operative reactions or infections. The use of OIC significantly reduced tunnel widening (p < 0.05) and improved graft maturation (p < 0.05). Patients treated with OIC had a significantly lower prevalence of ganglion cyst compared to the control group (p < 0.05). The use of OIC has measurable effects on the reduction of tunnel widening, improved graft maturation, and decreased size of ganglion cyst after ACL reconstruction. This study explored the utilization of biologics to minimize bone tunnel widening in ACL reconstruction surgery.

show abstract

Arthroscopic ACL reconstruction using patellar bone tendon autograft and Rigidfix fixation - A midterm functional outcome

Cited by 2 publications

References 30 publications

Tunnel Widening of Acl Reconstruction Augmented by an Platelet Rich Osteoconductive-Osteoinductive Allograft Compound: A Randomized Blind-Analysis Pilot Study

Tunnel Widening of Acl Reconstruction Augmented by an Platelet Rich Osteoconductive-Osteoinductive Allograft Compound: A Randomized Blind-Analysis Pilot Study

Effects of Platelet-Rich Osteoconductive–Osteoinductive Allograft Compound on Tunnel Widening of ACL Reconstruction: A Randomized Blind Analysis Study

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