Central to the institutional turn in regional economic analysis is the concept of relational assets. If neoclassical approaches to regional economic development focused their attention on factors of production, resource endowments, and comparative advantage, the turn to the concept of relational assets focused on the ways in which interfirm behavior and competitiveness also depend on intangible, behavioral, and normative practices. Such assets have been identified with multinational businesses, global value chains, and global production networks, as well as localized networks of interaction, familiarity, and trust, such as metropolitan regions, industrial districts, and clusters. Relational assets act as differential social and spatial resources that provide advantages (or, in their absence, disadvantages) to businesses in specific locales and networks.