Artificial composite bone as a model of human trabecular bone: The implant–bone interface

Grant, Jason A.; Bishop, Nick; Götzen, Nils; Sprecher, Christoph M.; Honl, M.; Morlock, Michael M.

doi:10.1016/j.jbiomech.2006.04.007

Cited by 142 publications

(83 citation statements)

References 8 publications

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“…Instead of real bone, a composite bone specimen has been used that possibly cannot reproduce all in-vivo conditions, precisely. However, composite bone has been successfully used in several biomechanical studies, since inter-specimen variability is small and therefore provides more consistency among specimens than cadaveric bone [29][30][31][32][33][34][35][36][37]47]. The support structure is still not entirely representative of the in-vivo situation, where there are no rigid constraints.…”

Section: Discussionmentioning

confidence: 99%

Experimental validation of numerically predicted strain and micromotion in intact and implanted composite hemi-pelvises

Ghosh

Gupta

Dickinson

et al. 2012

Proc Inst Mech Eng H

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The failure mechanisms of acetabular prostheses may be investigated by understanding the changes in load transfer due to implantation, and analysis of the implant-bone micromotion. Computational finite element (FE) models allow detailed mechanical analysis of the implant-bone structure, but their validity must be assessed as part of a verification process before they can be employed in pre-clinical investigations. To this end, in the present study, FE models of composite hemi-pelvises, intact and implanted with an acetabular cup, were experimentally verified. Strains and implant-bone micromotions in the hemi-pelvises were compared with those predicted by the equivalent FE models. Regression analysis indicated close agreement between the measured and FE strains, with a high correlation coefficient (0.95-0.98), a low standard error of the estimate (36-53µε) and a low error in regression slope (7-11%). Measured micromotions along three orthogonal directions were small, less than 30µm, whereas the FE predicted values were found to be less than 85µm. Although the trends were similar, the observed deviations may be due to estimation of the interfacial press-fit used in the FE model, and additional artefacts in experimental micromotion measurement which are avoided in the FE model. This supports the FE model as a valid predictor of the experimentally measured strain in the composite pelvis models, confirming its suitability for further computational investigations on acetabular prostheses. 4 IntroductionLoosening of the acetabular prosthesis is responsible for the majority of failures in total hip replacement [1][2][3][4]. However, biomechanical investigations into phenomena such as the load transfer mechanism across the pelvis and the acetabular reconstruction remain relatively under-investigated as compared to the femoral component. Measurement of such phenomena across the intact and implanted bones would be a useful step forward in the analysis of acetabular failure, and to date this has commonly been evaluated using finite element (FE) analysis [5][6][7][8][9][10][11]. The validity of the FE model generation process should be assessed using quantitative comparisons between computational predictions and experimental results [Anderson et al., 2007].Researchers have investigated the strain/stress distributions in the intact pelvis by comparing experimentally measured strains with those predicted by the equivalent FE model [5,7,10]. However, all these studies featured large areas of rigid fixation, which may not be fully representative of in-vivo bone support. Moreover, there is a scarcity of experimental data on strain measurement in intact and implanted pelvises which could be used to identify potential links between changes in strain distribution due to implantation and clinical failure mechanisms [12][13][14].The initial fixation of an uncemented implant is dependent on the primary stability, which is usually indicated by the amount of micromotion at the implant-bone interface, prior to bone-ingrowth, induc...

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Section: Discussionmentioning

confidence: 99%

Experimental validation of numerically predicted strain and micromotion in intact and implanted composite hemi-pelvises

Ghosh

Gupta

Dickinson

et al. 2012

Proc Inst Mech Eng H

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“…Interfaces between crown, abutment and implant are modeled as bonded contact. The interface between bone and implant is modeled as frictional contact with a friction coefficient [6,7]. Two forces of 100 N are applied on the occlusal area.…”

Section: Boundary Conditionsmentioning

confidence: 99%

Patient specific root-analogue dental implants – additive manufacturing and finite element analysis

Gattinger

Bullemer

Harrysson

2016

Current Directions in Biomedical Engineering

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Aim of this study was to prove the possibility of manufacturing patient specific root analogue twopart (implant and abutment) implants by direct metal laser sintering. The two-part implant design enables covered healing of the implant. Therefore, CT-scans of three patients are used for reverse engineering of the implants, abutments and crowns. Patient specific implants are manufactured and measured concerning dimensional accuracy and surface roughness. Impacts of occlusal forces are simulated via FEA and compared to those of standard implants.

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“…The friction coefficient was set at 0.6. 19,31 The material properties of the model were set as homogeneous and isotropic with linear elasticity. The finite element model was constructed from 4-node tetrahedral elements and it incorporated approximately 814 000 elements and 161 000 nodes.…”

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confidence: 99%

Micromotion analysis of different implant configuration, bone density, and crestal cortical bone thickness in immediately loaded mandibular full‐arch implant restorations: A nonlinear finite element study

Sugiura

Yamamoto

Horita

et al. 2017

Clin Implant Dent Rel Res

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Artificial composite bone as a model of human trabecular bone: The implant–bone interface

Cited by 142 publications

References 8 publications

Experimental validation of numerically predicted strain and micromotion in intact and implanted composite hemi-pelvises

Experimental validation of numerically predicted strain and micromotion in intact and implanted composite hemi-pelvises

Patient specific root-analogue dental implants – additive manufacturing and finite element analysis

Micromotion analysis of different implant configuration, bone density, and crestal cortical bone thickness in immediately loaded mandibular full‐arch implant restorations: A nonlinear finite element study

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