Asbestos-Related Lung Disease: A Pictorial Review

Norbet, Christopher; Joseph, A.E.A.; Rossi, Santiago S.; Bhalla, Sanjeev; Gutiérrez, Fernando R.

doi:10.1067/j.cpradiol.2014.10.002

Cited by 56 publications

(50 citation statements)

References 32 publications

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“…They induce a range of non-malignant inflammatory diseases (asbestosis) due to formation of plaques in the pleura and to permanent fibrosis, which promote carcinogenesis (3). Malignant ARDs include bronchogenic carcinoma and mesothelioma of the pleura (80-90%), peritoneum (10-15%), and other mesothelial surfaces (< 5%) (4).…”

Section: Introductionmentioning

confidence: 99%

Progress of research on microRNAs with diagnostic value in asbestos exposure: A call for method standardization

Micolucci

Rippo

Olivieri

et al. 2017

BST

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Section: Introductionmentioning

confidence: 99%

Progress of research on microRNAs with diagnostic value in asbestos exposure: A call for method standardization

Micolucci

Rippo

Olivieri

et al. 2017

BST

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“…Fibers longer than 10 microns, stop at the alveolar level where they can cause asbestos-related alveolitis (114,115). …”

Section: Fibersmentioning

confidence: 99%

Occupational exposure to carcinogens: Benzene, pesticides and fibers

Falzone

Marconi

Loreto

et al. 2016

Molecular Medicine Reports

100

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It is well known that the occupational exposure to contaminants and carcinogens leads to the development of cancer in exposed workers. In the 18th century, Percivall Pott was the first to hypothesize that chronic exposure to dust in the London chimney sweeps was associated with an increased risk of developing cancer. Subsequently a growing body of evidence indicated that other physical factors were also responsible for oncogenic mutations. Over the past decades, many carcinogens have been found in the occupational environment and their presence is often associated with an increased incidence of cancer. Occupational exposure involves several factors and the association between carcinogens, occupational exposure and cancer is still unclear. Only a fraction of factors is recognized as occupational carcinogens and for each factor, there is an increased risk of cancer development associated with a specific work activity. According to the International Agency for Research on Cancer (IARC), the majority of carcinogens are classified as ‘probable’ and ‘possible’ human carcinogens, while, direct evidence of carcinogenicity is provided in epidemiological and experimental studies. In the present review, exposures to benzene, pesticides and mineral fibers are discussed as the most important cancer risk factors during work activities.

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“…In contrast, pleural thickening secondary to chronic inflammation predominantly involves the visceral pleura, which contributes to a restrictive pattern and impaired ventilation. Pleural thickening does not calcify and can blunt the costophrenic angles 1. Rounded atelectasis is an atelectatic area of the lung adjacent to the pleural thickening and is strongly associated with asbestos exposure (figure 3).…”

Section: Descriptionmentioning

confidence: 99%

“…Round atelectasis sometimes spontaneously resolves. It is metabolically inactive on PET-CT imaging 1. A fibrotic band is a thickening of the visceral pleura resulting in a pleural-parenchymal fibrous band radiating from the pleura (figure 1).…”

Section: Descriptionmentioning

confidence: 99%