Aseptic and Viral Meningitis

Sawyer, Mark H.; Rotbart, Harley A.

doi:10.1016/b978-0-7020-3468-8.50051-1

Cited by 3 publications

(1 citation statement)

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“…Neonates are more at the increased risk of severe systemic diseases, particularly nervous system involvement with Herpes simplex virus (HSV) (3). It has been reported that the herpes virus family collectively involved about 4% of viral meningitis cases which more are cases caused by HSV-2.…”

Section: Introductionmentioning

confidence: 99%

Herpes Simplex Virus Meningitis in Children in South East of Caspian Sea, Iran

Azadfar

Cheraghali

Moradi

et al. 2014

Jundishapur J Microbiol

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Background:Herpes simplex virus (HSV) is a member of Herpesviridae and a leading cause of human viral diseases. Meningitis occurs as a complication of HSV-1 or HSV-2 primary infection.Objectives:We aimed to evaluate HSV meningitis in children in Gorgan province, Iran.Patients and Methods:Forty-five cerebrospinal fluid samples were taken from children referred with meningitis symptoms. Samples with negative bacterial culture results were tested for viral, biochemical and cytological assays. DNA extraction and PCR were performed.Results:HSV-1 detected in 4 (8.8%) samples without any HSV-2 infections. Cases with positive results had fever and CSF pleocytosis. Vomiting, headache and higher count of WBC were observed in 3, 2 and 3 cases respectively. The cerebrospinal fluid (CSF) glucose and protein levels were normal and 3 cases showed positive C-reactive protein (CRP) results. Also erythrocyte sedimentation rate (ESR) was higher than normal in all positive cases.Conclusions:Distribution of HSV types in children with meningitis in our area predominantly was type 1 compared with type 2, which has been reported more in other area.

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Section: Introductionmentioning

confidence: 99%