Asian Indians, coronary artery disease, and physical exercise

Dhawan, J; Bray, Colin

doi:10.1136/hrt.78.6.550

Cited by 49 publications

(32 citation statements)

References 7 publications

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“…Reduced physical activity has been demonstrated in UK Asians compared with white Caucasians (Table 1) [5,16,17,44]. A recent systematic literature review of studies describing levels of physical activity and fitness in UK south Asians identified 17 studies; all reported lower levels in south Asians compared with the general population [45].…”

Section: Reduced Physical Activitymentioning

confidence: 99%

Type 2 diabetes and cardiovascular risk in the UK south Asian community

et al. 2006

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A popular hypothesis for the greater prevalence of type 2 diabetes and cardiovascular disease in UK south Asians is that they have an increased susceptibility of developing insulin resistance in response to certain environmental factors, including obesity and adoption of a sedentary lifestyle. Insulin resistance is postulated as a central feature of the metabolic syndrome, culminating in type 2 diabetes, atherosclerotic vascular disease and CHD; a pathway potentially accelerated by migration/ urbanisation. We describe and compare the prevalence of type 2 diabetes, cardiovascular disease and their associated risk factors in UK south Asian and white Caucasian populations to determine possible reasons for the increased preponderance of these diseases in south Asians, and highlight key evidence for optimal risk factor management. Finally, we describe a UK communitybased programme that attempts to reduce the morbidity and mortality from type 2 diabetes and cardiovascular disease in south Asians through a new approach to management.

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Section: Reduced Physical Activitymentioning

confidence: 99%

Type 2 diabetes and cardiovascular risk in the UK south Asian community

et al. 2006

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“…British Asians have been reported to undertake low levels of physical activity 42,173 and have a high consumption of fatty food. 174 The Asian patients we interviewed showed an understanding of the advice about eating a healthier diet and were making significant changes to their diet.…”

Section: South Asians and Lifestyle Changementioning

confidence: 99%

The Birmingham Rehabilitation Uptake Maximisation Study (BRUM). Home-based compared with hospital-based cardiac rehabilitation in a multi-ethnic population: cost-effectiveness and patient adherence

Jolly¹,

Taylor²,

Gy³

et al. 2007

Health Technol Assess

174

262

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“…Lack of exercise is another risk factor for T2DM. The 2004 Health Survey for England data reported lower levels of physical activity in South Asian groups compared with the general UK population and other ethnic minority groups (77), and other studies showed similar results in migrant and urban South Asians (6,15,82,83,84,85,86,87). This low level of physical activity is already present in children and adolescents (77,85,88,89,90,91).…”

Section: Diet and Exercisementioning

confidence: 47%

MECHANISMS IN ENDOCRINOLOGY: Pathogenesis of type 2 diabetes in South Asians

Bakker

Sleddering

Schoones

et al. 2013

European Journal of Endocrinology

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The risk of developing type 2 diabetes mellitus (T2DM) is exceptionally high among both native and migrant South Asians. T2DM occurs more often and at a younger age and lower BMI, and the risk of coronary artery and cerebrovascular disease, and renal complications is higher for South Asians compared with people of White Caucasian descent. The high prevalence of T2DM and its related complications in South Asians, which comprise one-fifth of the total world's population, poses a major health and socioeconomic burden. The underlying cause of this excess risk, however, is still not completely understood. Therefore, gaining insight into the pathogenesis of T2DM in South Asians is of great importance. The predominant mechanism, in this ethnicity seems to be insulin resistance (IR) rather than an impaired b-cell function. In this systematic review, we describe several possible mechanisms that may underlie or contribute to the increased IR observed in South Asians.

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Asian Indians, coronary artery disease, and physical exercise

Cited by 49 publications

References 7 publications

Type 2 diabetes and cardiovascular risk in the UK south Asian community

Type 2 diabetes and cardiovascular risk in the UK south Asian community

The Birmingham Rehabilitation Uptake Maximisation Study (BRUM). Home-based compared with hospital-based cardiac rehabilitation in a multi-ethnic population: cost-effectiveness and patient adherence

MECHANISMS IN ENDOCRINOLOGY: Pathogenesis of type 2 diabetes in South Asians

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