Central obesity in the subgroups of Asians studied showed a close association with hyperinsulinaemia and the risk of coronary artery disease. A predisposition to insulin resistance and its metabolic abnormalities in this group of Asians seems to be genetically determined, environmental changes after migration having only a small additional effect.

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Objective-To evaluate the relation of physical activity to diVerent clinical and biochemical risk factors for coronary artery disease among people from diVerent ethnic groups with angiographically proven coronary artery disease. Subjects-British Asians, Indian Asians, and white people suVering from coronary artery disease, and their respective controls. Interventions