Aspartic acid based metal–organic frameworks with dual function of NADH peroxidase and glycerol dehydrogenase-mimicking activities

Abstract

CuAsp with a fiber-like structure exhibited both NADH peroxidase- and glycerol dehydrogenase (GlyDH)-mimetic activities.

Recent Development of Copper‐Based Nanozymes for Biomedical Applications

“…In a separate study, Liu et al. [ 31 ] synthesized copper aspartic acid (CuAsp) metal‐organic frameworks (MOFs) by altering the functional groups of ligands and observed that both the length of the carbon chain and the number of amino groups in the ligands influenced the catalytic activity. The results demonstrated that CuAsp MOF exhibited the highest catalytic activity when L‐aspartic acid was used as the ligand, owing to the strong coordination ability of L‐aspartic acid with Cu 2+ .…”

Construction of hierarchically chiral metal–organic frameworks for fast and mild asymmetric catalysis

“…L-Aspartic acid (ASP) is regarded as a suitable linker, which not only provides flexibility and donates electrons to the metal in the framework, but also presents optical activity, enabling the preparation of chiral materials. [23][24][25] The benefits of utilizing this functional biomolecule include its multiple coordination sites, hydrogen bonding, aliphatic backbone, and chirality. [26][27][28] Furthermore, the natural abundance and com-mercial availability of L-aspartic acid make it an appropriate multifunctional molecule for the preparation of bioMOFs.…”

“…32 Also, because the uncoordinated amino groups pointed toward the pores, MIP-202(Zr) presented different behavior from that of the Zr-fumarate compound as a Lewis base and Brønsted acid. 24 The Brønsted acidity of MIP-202 originated from the conversion of the NH 2 group of l -aspartic acid to NH 3 + under acidic condition. Indeed, because of the production of HCl upon the hydrolysis of ZrCl 4 , the NH 3 + Cl − -ASP salt moiety was obtained.…”

Iron-incorporated metal–organic frameworks for oxidative cleavage of trans-anethole to p-anisaldehyde

“…31,32 Connected and extended through coordination bonds between metal ions and organic ligands, MOFs share similarities with natural enzymes in terms of size, morphology, and surface charge. [33][34][35] Additionally, MOFs can mimic the structure of the active center of natural metalloenzymes. [36][37][38][39] Iron-based catalysts have attracted attention due to their low toxicity and low cost.…”