2008
DOI: 10.1590/s1415-52732008000500009
|View full text |Cite
|
Sign up to set email alerts
|

Aspectos atuais da relação entre exercício físico, estresse oxidativo e magnésio

Abstract: Este trabalho visa a contribuir com informações atualizadas sobre a relação entre exercício, estresse oxidativo e magnésio. São escassos os trabalhos que discutem a produção de radicais livres nesse contexto. A deficiência de magnésio altera a fluidez das membranas celulares e mitocondriais e promove perturbações na homeostase do cálcio e na atividade das defesas antioxidantes. No exercício, a falta de magnésio nos tecidos musculares os torna mais suscetíveis à infiltração de macrófagos e neutrófilos e ao romp… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
2
0
15

Year Published

2012
2012
2023
2023

Publication Types

Select...
5
2
1

Relationship

0
8

Authors

Journals

citations
Cited by 17 publications
(17 citation statements)
references
References 44 publications
0
2
0
15
Order By: Relevance
“…53,54 Hypomagnesemia favors the infiltration of neutrophils and macrophages in the affected cells, which potentiates the activity of the enzyme nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase), increasing the production of the superoxide radical. 46,55 Hypomagnesemia also contributes to reduce the expression and activity of antioxidant enzymes, such as glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase (CAT), and cellular and tissue antioxidant concentrations, as well as increases the production of hydrogen peroxide by inflammatory cells. 11,56 Combined with this, in the presence of hypomagnesemia, intracellular ionic calcium contributes to the excessive production of uric acid and hydroxyl radical, which reacts with nitric oxide, which is also high in hypomagnesemia, forming peroxynitrite.…”
Section: Metabolic and Physiological Aspects Of Magnesiummentioning
confidence: 99%
“…53,54 Hypomagnesemia favors the infiltration of neutrophils and macrophages in the affected cells, which potentiates the activity of the enzyme nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase), increasing the production of the superoxide radical. 46,55 Hypomagnesemia also contributes to reduce the expression and activity of antioxidant enzymes, such as glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase (CAT), and cellular and tissue antioxidant concentrations, as well as increases the production of hydrogen peroxide by inflammatory cells. 11,56 Combined with this, in the presence of hypomagnesemia, intracellular ionic calcium contributes to the excessive production of uric acid and hydroxyl radical, which reacts with nitric oxide, which is also high in hypomagnesemia, forming peroxynitrite.…”
Section: Metabolic and Physiological Aspects Of Magnesiummentioning
confidence: 99%
“…A deficiência dietética de magnésio é positivamente correlacionada ao aumento da peroxidação lipídica e à diminuição da atividade antioxidante, podendo agravar a resposta inflamatória comumente observada em atletas 24 . Além disso, altera a fluidez das membranas celulares e mitocondriais promovendo perturbações na homeostase do cálcio.…”
Section: Discussionunclassified
“…Desta forma, na depleção de magnésio, o cálcio intracelular eleva-se, podendo causar cãimbras musculares, hipertensão, vasoespasmos coronarianos e cerebrais. No desempenho físico, a falta de magnésio traduz-se em lesões musculares mais sérias, ficando os músculos mais suscetíveis à infiltração de macrófagos e neutrófilos e ao rompimento do sarcolema, dificultando o processo de regeneração e podendo ocasionar declínio no desempenho físico 24 . Como mostrado nas tabelas 4 e 5, o magnésio teve seu consumo menor do que o recomendado tanto nos homens quanto nas mulheres, resultado igualmente observado em futebolistas 25 .…”
Section: Discussionunclassified
“…If the action of these free radicals will be beneficial or deleterious for the organism will depend on the antioxidants activity, which are substances that suppress these radicals and their harmful effects [41]. Free radicals are naturally produced by the organism and are often of great use, as in the activation of the immunological system, participation on the detoxification of drugs and in the production of nitric oxide, which is fundamental for relaxing blood vessels [42].…”
Section: Physical Exercise Antioxidants and Oxidative Stressmentioning
confidence: 99%