Aspectos clínico-epidemiológicos de la toxoplasmosis en pacientes que consultan por problemas de visión

Samudio, Margarita; Acosta, María Eugenia; Castillo, V Lisset; Guillén, Yvalena; Licitra, G.; Aria, Laura; Cibils, Pablo; Rojas, Alejandra; Cibils, D; Meza, Teresa; Infanzón, Belén; Kaspar, Herminia Miño de

doi:10.4067/s0716-10182015000700007

Cited by 10 publications

(10 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, such spatial methodology should be used for other zoonotic diseases to holistically evaluate the role of the household setting on the disease cycle and epidemiology. Despite previous reports [53–59], the consumption of raw meat and unwashed or raw fruits or vegetables were not associated herein with T . gondii seropositivity in human beings.…”

Section: Discussioncontrasting

confidence: 90%

Spatial and simultaneous representative seroprevalence of anti-Toxoplasma gondii antibodies in owners and their domiciled dogs in a major city of southern Brazil

et al. 2017

View full text Add to dashboard Cite

Toxoplasmosis, caused by Toxoplasma gondii, has traditionally been considered an important water and foodborne protozoonosis with important public health considerations. Although felids play a well-established role as definitive hosts, canine epidemiological involvement in the parasite’s life cycle remains questionable and controversial. The increasing closeness of the human-dog bond, particularly seen in urban settings, has been recognized as a historically unprecedented worldwide movement. Sharing daily lives in the same households, dogs may be exposed to similar associated risks of T. gondii infection as their owners. Thus, epidemiological assessment of the intra-domiciled environment, especially among socio-economically different human populations, may provide novel information regarding the actual role of dogs in animal and human toxoplasmosis. Despite spatial approaches being recently used for other water and foodborne diseases, no study has been conducted on the simultaneous spatial seroprevalence of both human and animal IgG anti-T. gondii antibodies in urban areas of major cities. Accordingly, the aim of the present study was to assess the seroprevalence and associated variables of Toxoplasma infection in owners and their domiciled dogs in Londrina, southern Brazil. Human and canine seroprevalence rates and variables associated with seroprevalence were investigated through representative random sampling among 564 households, which included 597 owners and 729 dogs. Overall, statistically significant differences between the seroprevalence of human and dog anti-T. gondii antibodies were found by Immunofluorescence Antibody Testing in 248/597 (41.54%) owners and 119/729 (16.32%) dogs. Through multiple analysis, significant concomitant variables for seropositivity of household individuals (people and dogs) were determined, including public sewer service, yard cleaning frequency, and having a dirty yard. Although no statistically significant multiple logistic model was observed among owners, univariate analysis detected associations with monthly income, soil contact, and occupation. Among dogs, the absence of other dogs and the absence of a dirty yard were concomitant significantly protective associated factors. Age differences between seropositive and seronegative individuals was significant only for human beings, with the median age of negative individuals significantly higher than positive individuals. Although no spatial clusters were identified for humans or residences, a significant cluster was identified for dogs. In conclusion, characteristics of urban toxoplasmosis may include significantly higher owner seroprevalence than their owned dogs, with canine seroprevalence directly associated with having more dogs and a dirty backyard, and spatial differences in both human and dog exposures. Although not a good indicator for human foodborne diseases, dogs may be a reliable sentinel for environmental infection. Moreover, such a holistic approach may provide crucial information for more focused prevention and...

show abstract

Section: Discussioncontrasting

confidence: 90%

Spatial and simultaneous representative seroprevalence of anti-Toxoplasma gondii antibodies in owners and their domiciled dogs in a major city of southern Brazil

et al. 2017

View full text Add to dashboard Cite

show abstract

“…The prevalence of toxoplasmosis was evaluated in ocular patients, the result demonstrated that around half of patients were infected with toxoplasmosis, but most cases were chronic and only a couple of cases were acute or recurred with low IgM titer, based on serological test, It was found 43.1% were positive for IgG, while 1.1% for IgM. These findings could be due to the patient's visit ophthalmologist weeks or months after T. gondii infection and the titer of IgM In the present investigation, from 80 seropositive patients, only 10 (2 males and 8 females) (12.5%) presented ocular toxoplasmosis as an old or active lesion, this result closely resemble with the result of Samudio et al (2015) in Brazil whom recorded 6 (5 males and 1 females) (8.9%) of ocular toxoplasmosis lesion among 80 ocular toxoplasmosis patients [23]. According to a new research that was done in 2020, the prevalence of retinochoroidal scars was higher in female patients than in males [24].…”

Section: Discussionsupporting

confidence: 75%

“…However, it may be related to the host when the patient re-infected after consuming contaminated foods, bursting the old scar after altering in host immune status or the new strain can be blamed for the recurrence. People who did not get effective treatment have a greater chance of recurrence and producing new lesions beside the old ones [31,32], and continuous multiplication of the parasite within the tissue cyst and rupturing as a result after a long time of infection and this leads to the formation of new lesions [33].…”

Section: Discussionmentioning

confidence: 99%

Seroprevalence of Toxoplasma gondii among ocular infection patient in Shahid Dr. Aso Hospital in Sulaimani City, Iraq

Karim

Azeez²,

Abdullah

2022

ijhs

View full text Add to dashboard Cite

Toxoplasma gondii is an intracellular protozoan parasite that causes ocular toxoplasmosis with most complications such as developing eye lesions and impaired vision. During the period from October 2021 to April 2022, a total of 174 blood samples were taken from ocular infected patients whom visited Shahid Dr. Aso Hospital in Sulaimani City, Iraq. These samples were tested serologically for detection of anti-Toxoplasma gondii antibodies (IgG and IgM) with both imunochromatograhpy (rapid test) and ELISA. The serological test demonstrated that 63 IgG (36.2%) and 4 IgM (2.2%) were positive by rapid test imunochromatograhpy. While, 80 IgG (45.9%) and 2 IgM (1.1%) were positive by ELISA. Most of the infections (58.75%) were between 50-69 years old. All patients (80) were examined for intraocular toxoplasmosis lesion, only 10 patients (12.5%) including 2 males (2.5%) and 8 females (10%) had ocular toxoplasmosis lesions. Most of the lesions were scars (old type) while, in some patients they were active lesions. The types of lesions, numbers per each eye, lesion diameter and comparison with the IgG and IgM titers were demonstrated.

show abstract

“…Sin embargo, cuando se compara con otro estudio realizado también en Paraguay pero en pacientes con problemas de visión, los resultados son similares, considerando que en ese estudio la frecuencia de toxoplasmosis ocular fue de 7,5% (6/80), y la frecuencia en los 67 pacientes seropositivos fue del 8,9% (13). Las cifras de la frecuencia de toxoplasmosis ocular en otros países de América del Sur, son también similares, así en Colombia, De la Torre et al en una muestra poblacional de 200 individuos entre estudiantes y trabajadores en una Universidad del Quindío, con edades comprendidas entre los 18 y 45 años y encontraron que el 6% de ellos (12 pacientes) presentaba cicatrices retinianas por toxoplasma (4); adicional a esto, otras observaciones han surgido a partir de los estudios poblacionales con muestras significativas de 1042 personas en un área rural Erechim con alta tasa de toxoplasmosis (una ciudad agrícola situada en una región del sur de Brasil [Rio Grande do Sul]), mostrando una prevalencia del 17% de lesiones oculares que eran compatibles con toxoplasmosis (8) (y predomina el tipo I T. gondii).…”

Section: Discussionunclassified

Prevalence of Toxoplasma retinochoroidal scars in a Paraguayan population

Hernández

Gómez

Samudio

et al. 2016

Mem. Inst. Investig. Cienc. Salud

Self Cite

View full text Add to dashboard Cite

Aspectos clínico-epidemiológicos de la toxoplasmosis en pacientes que consultan por problemas de visión

Cited by 10 publications

References 26 publications

Spatial and simultaneous representative seroprevalence of anti-Toxoplasma gondii antibodies in owners and their domiciled dogs in a major city of southern Brazil

Spatial and simultaneous representative seroprevalence of anti-Toxoplasma gondii antibodies in owners and their domiciled dogs in a major city of southern Brazil

Seroprevalence of Toxoplasma gondii among ocular infection patient in Shahid Dr. Aso Hospital in Sulaimani City, Iraq

Prevalence of Toxoplasma retinochoroidal scars in a Paraguayan population

Contact Info

Product

Resources

About