Aspects of Antifungal Potential of Ethnobotanically Known Medicinal Plants

Sati, S. C.; Joshi, Savita

doi:10.3923/rjmp.2011.377.391

Cited by 26 publications

(15 citation statements)

References 33 publications

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“…Volatile oil is the secondary metabolites that play many important roles in human daily life, such as perfumery, spices, essence, medicine, aromatherapy, insect repellent, and also as fungicide [1]. Many medicinal plants contain volatile oil; many of them have been traditionally used in cut healing or as natural preservatives due to their capacity to control the growth of bacteria and or fungi [2]. Coumarin is reported to be one of the antifungal compounds present in the leaves of Ageratum conyzoides in addition to the volatile oil components.…”

Section: Introductionmentioning

confidence: 99%

Plant Secondary Metabolites for Antifusarium and Antiphytophthora

Sukrasno¹

2018

Fusarium - Plant Diseases, Pathogen Diversity, Genetic Diversity, Resistance and Molecular Markers

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Plants produce secondary metabolites that are essential for survival of the producing plants such as to attract insect for pollination and defend against pest and environmental stress. Plant secondary metabolites are widely exploited by the mankind especially for medicine, one of which is to protect against infection by microorganism including fungi. Many medicinal plants have been traditionally used and/or studied for the fungicidal activity. Most of the plants studied or traditionally used as antifungi show antiphytophthora activity and some of them also active as antifusarium. Higher concentration plant extract is needed to inhibit the growth of Fusarium than Phytophthora. Considering the concentration in plant and activity as antifungi, eugenol is considered to be the most effective to be used as antiphytophthora and antifusarium. The presence of aromatic moiety, orthodioxy substitution, and double bond in the terminal of site chain is considered to be essential for the antifungal activity of the eugenol derivative.

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Section: Introductionmentioning

confidence: 99%

Plant Secondary Metabolites for Antifusarium and Antiphytophthora

Sukrasno¹

2018

Fusarium - Plant Diseases, Pathogen Diversity, Genetic Diversity, Resistance and Molecular Markers

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“…Wild plants have always been a major source for primary health care and other necessities of daily life for local communities throughout the world, an indication that medicinal plants can provide the best alternative source to obtain a variety of drugs. Drugs of natural origin now play an ever more important role in medical and healthcare services because metabolites produced by plants constitute a major source of bioactive substances which can be used as an alternative for cheap and effective herbal drugs against common infections [3].…”

Section: Introductionmentioning

confidence: 99%

In-Vivo Toxicity Assessment of Stem Bark Extracts of Spondias mombin (Linn) on Male and Female Albino Rats

Ot¹

2018

OAJPR

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Spondias mombin is depends on for various herbal remedies for the treatment of numerous health conditions. This study is to evaluate the In-vivo toxic effect of Stem bark extracts of Spondias mombin on in male and female albino rats. In-vivo toxicity test was carried out with modified Lorke's method. Forty two (42) male and female albino rats weighing between 120-180g were used for the sub-chronic study. The rats were divided into five groups A-D (n=12). The albino rats were divided into four groups labelled A, B, C, and D with group A, B, and C consisting of 12 rats each, while the remaining 6 rats served as control which were placed in group D. Group A, B and C were fed with 200 mg/kg and 500 mg/kg body weight doses of crude aqueous, ethanol and ethyl acetate stem bark extracts of S.mombin, respectively with the aid of an oral gastric tube. Treatments lasted for twenty one days (21). Acute toxicity test carried out showed that stem bark extracts of S. mom bin did not produce mortality in rats. Significant (p<0.05) reduction in brain and kidney weights was observed in group C treated with 200 mg/kg and 500mgkg-1 of crude ethyl acetate stem bark extracts of S. mombin.Similarly, significant (p<0.05) reduction was observed in spleen weights in groups C and D that were treated with 200 mg/kg and 500mgkg-1 of both extracts. The levels of LDL (p<0.001) and ALP (p<0.05) were significantly reduced. It can be concluded that, this result suggests that, the use of the stem bark extracts of S.mombin is relatively safe.

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“…The extracts of many plants/herbs have been shown to exert biological activity in vitro or in vivo, justifying research on traditional medicine that focuses on the characterization of antifungal activity of these plants in India that have a diverse flora and a rich tradition for use of medicinal plants. Since plants produce a variety of compounds with antimicrobial properties, it is expected that screening programs for some under-represented targets, such as antifungal activity, may yield important compounds for antimicrobial remedies (Ahmad & Beg 2001, Sati & Joshi 2011. Gymnosperms are almost a neglected group of plants in Himalayan region so as the antimicrobial activity of these plants have not been explored adequately so far .…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Kumaun Himalayan Biota orientalis Endl. leaves extracts against pathogenic fungi

Joshi

Sati²,

Kumar³

2016

IJPT

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An increasing demand for natural plant products has shifted the attention from synthetic to natural antifungal agents. This study was carried out to evaluate the antifungal activity of methanol, ethanol, chloroform, hexane and water extracts of Biota orientalis Endl. leaves, a Kumaun Himalayan gymnospermic plant. The antifungal potential of all extracts of B. orientalis were tested against seven different fungal strains (Alternaria alternata, Colletotrichum falcatum, Fusarium oxysporum, Pyricularia oryzae, Sclerotinia rolfsii, Sclerotinia sclerotiorum and Tilletia indica) using agar-well diffusion method. The ethanol extract was found most active against all the pathogens tested (Percent inhibition, 27-59%) followed by hexane extract (Percent inhibition, 31-58%) and methanol extract (27-57%) while chloroform and aqueous extracts were found totally inactive against all the tested fungal strains, only chloroform extract showed inhibitory activity against S. rolfsii (% inhibition, 58%). The inhibitory activity of these extracts was found very effective as compared to Clotrimazol, standard antifungal agent that was used as positive control against tested fungal strains.

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Aspects of Antifungal Potential of Ethnobotanically Known Medicinal Plants

Cited by 26 publications

References 33 publications

Plant Secondary Metabolites for Antifusarium and Antiphytophthora

Plant Secondary Metabolites for Antifusarium and Antiphytophthora

In-Vivo Toxicity Assessment of Stem Bark Extracts of Spondias mombin (Linn) on Male and Female Albino Rats

Efficacy of Kumaun Himalayan Biota orientalis Endl. leaves extracts against pathogenic fungi

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