Aspergillus fumigatus infection in a mega prosthetic total knee arthroplasty

Baumann, Patricia A; Cunningham, Benjamin; Patel, Nishitkumar S.; Finn, Henry A.

doi:10.1054/arth.2001.21505

Cited by 31 publications

(13 citation statements)

References 14 publications

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“…This patient presented with a popliteal cyst 27 months after surgery and was cured with a 12-week course of amphotericin B in combination with surgical debridement and prosthesis removal. Other similar cases have also been published [157,158].…”

Section: Other (Rare) Clinical Presentationssupporting

confidence: 64%

Aspergillosis in Surgical Patients

Pasqualotto

2009

Aspergillosis: From Diagnosis to Prevention

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Most physicians will promptly consider the possibility of invasive aspergillosis in high-risk patients in the presence of an appropriate clinical syndrome. Aspergillosis will however only rarely be listed amongst the possible aetiologies of surgical site infections, although hundreds of cases have been published so far. This chapter reviews the current literature on post-operative aspergillosis. A few illustrative clinical cases are also shown. In most patients, the source was presumed to be airborne infection during the surgical procedure. Diagnosis relies on a high index of suspicion and treatment usually requires a combination of medical and surgical interventions. Prevention of post-operative aspergillosis requires special care with the ventilation system in the operating room.

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Section: Other (Rare) Clinical Presentationssupporting

confidence: 64%

Aspergillosis in Surgical Patients

Pasqualotto

2009

Aspergillosis: From Diagnosis to Prevention

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“…Rhodotorula minuta was reported as the cause of a periprosthetic infection in one case report 41 . In the remaining three reported cases, Aspergillus species (Aspergillus fumigatus and Aspergillus niger) was the causative pathogen 8,9,22 . A similar organism profile was noted in the present report (Fig.…”

Section: P Eriprosthetic Infection Caused By Fungal Pathogens Is Rarementioning

confidence: 99%

Microbiological, Clinical, and Surgical Features of Fungal Prosthetic Joint Infections: A Multi-Institutional Experience

Azzam

Parvızı

Jungkind

et al. 2009

Journal of Bone and Joint Surgery

183

264

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“…two-stage revision, with or without the use of a cement spacer; resection arthroplasty is the next favoured option. [6][7][8][9]21,22 In a multi-institutional retrospective study Azzam et al 8 reported recurrent infection in ten of 19 patients who had been treated with resection arthroplasty and delayed reimplantation of the prosthesis. In contrast, the largest multiinstitutional retrospective study, by Hwang et al, 9 with 30 fungal infections in TKRs, reported a rate of reinfection of 6.6%.…”

Section: Discussionmentioning

confidence: 99%

Single-stage revision for fungal peri-prosthetic joint infection

Klatte

Kendoff

Kamath

et al. 2014

The Bone & Joint Journal

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Fungal peri-prosthetic infections of the knee and hip are rare but likely to result in devastating complications. In this study we evaluated the results of their management using a single-stage exchange technique. Between 2001 and 2011, 14 patients (ten hips, four knees) were treated for a peri-prosthetic fungal infection. One patient was excluded because revision surgery was not possible owing to a large acetabular defect. One patient developed a further infection two months post-operatively and was excluded from the analysis. Two patients died of unrelated causes. After a mean of seven years (3 to 11) a total of ten patients were available for follow-up. One patient, undergoing revision replacement of the hip, had a post-operative dislocation. Another patient, undergoing revision replacement of the knee, developed a wound infection and required revision 29 months post-operatively following a peri-prosthetic femoral fracture. The mean Harris hip score increased to 74 points (63 to 84; p < 0.02) in those undergoing revision replacement of the hip, and the mean Hospital for Special Surgery knee score increased to 75 points (70 to 80; p < 0.01) in those undergoing revision replacement of the knee. A single-stage revision following fungal peri-prosthetic infection is feasible, with an acceptable rate of a satisfactory outcome.

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Aspergillus fumigatus infection in a mega prosthetic total knee arthroplasty

Cited by 31 publications

References 14 publications

Aspergillosis in Surgical Patients

Aspergillosis in Surgical Patients

Microbiological, Clinical, and Surgical Features of Fungal Prosthetic Joint Infections: A Multi-Institutional Experience

Single-stage revision for fungal peri-prosthetic joint infection

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