Aspiration cytology of head and neck masses

Russ, Joseph E.; Scanion, Edward F.; Christ, Miriam A.

doi:10.1016/0002-9610(78)90291-x

Cited by 45 publications

(14 citation statements)

References 6 publications

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“…As observed in studies by Smallman et al, 11 Jain et al, 13 Dhingra et al, 14 and Russ et al, 15 we also found that the most common lesions involving the pediatric head and neck are of lymph nodes, the most common being reactive lymphoid proliferations (72%, n = 412), followed by tubercular lymphadenitis (16%, n = 91) and granulomatous lymphadenitis (5.2%, n = 30). The present study did not make any attempt to categorize the type of reactive lymphadenopathy.…”

supporting

confidence: 85%

Evaluation of fine needle aspiration biopsy as a diagnostic tool in pediatric head and neck lesions

Dutta¹,

Awasthi²,

Agarwal³

et al. 2010

PLMI

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Background: Fine needle aspiration (FNA) biopsy is a well accepted diagnostic procedure and considered to be a valuable test for initial assessment of head and neck swellings in adults. The technique has gained popularity in the pediatric population over the last decade, with varying degrees of acceptance rates, accuracy, and results among pathologists. Objective: This study was performed to evaluate the utility of aspiration cytology as a first-line diagnostic tool in palpable head and neck masses in children, taking into account the diversity of lesions observed in this subset of the population. Cytologic analysis was correlated with histologic results for evaluating diagnostic accuracy wherever possible. The applicability of FNA biopsy in diagnosing pediatric malignant lesions was also evaluated. Methods: This retrospective study conducted from January 2008 to December 2009 screened all pediatric cases referred to the departments of pathology at two tertiary care hospitals in India. Data from a total of 662 children aged 0-15 years presenting with head and neck masses who underwent FNA biopsy were collected. Cytologic results were interpreted and analyzed according to anatomic site. The lesions were then categorized into inflammatory, infective, and neoplastic. Results: Of the 662 lesions, 23 cases were excluded due to inadequate material, thus the data for 639 cases were finally evaluated. Lymph node lesions predominated, accounting for 570 cases (89.2%), of which 412 (72%) cases were diagnosed as reactive and 91 (16%) cases as tubercular lymphadenitis. Other lesions aspirated were thyroid (18 cases, 2.8%), salivary gland (12 cases, 1.8%), and miscellaneous surface lumps (39 cases, 6.1%). Of all the cases, 628 (98.27%) were reported as benign and 11 (1.67%) as malignant. The positive predictive value of cytologic analysis in diagnosing malignancy was 100%, although exact typing of lesions was possible only on histopathologic examination. Conclusion: FNA biopsy is a sensitive and minimally invasive first-line investigation in the diagnosis of head and neck masses in children. It is highly accurate in isolating and determining potentially neoplastic lesions, thus guiding the way for cases which truly require excision biopsy or other second-line investigations.

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supporting

confidence: 85%

Evaluation of fine needle aspiration biopsy as a diagnostic tool in pediatric head and neck lesions

Dutta¹,

Awasthi²,

Agarwal³

et al. 2010

PLMI

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“…These findings are similar to the results of Engzell, et al, Gupta, et al and Ross, et 07. [21][22][23] A diagnostic test is considered satisfactory if its sensitivity and specificity are around 90%.…”

Section: Discussionmentioning

confidence: 99%

Correlation of fine needle aspiration cytology lymph node with histopathological diagnosis

Gupta

Singh

2016

Int J Res Med Sci

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INTRODUCTIONFine Needle Aspiration technique was described for the first time by Greig and Gray in 1904. Since the mid-1960's, it has been increasingly used and a high degree of accuracy has been achieved.l Lymphadenopathy is one of the commonest presenting symptoms of all age groups attending out door. The etiology can vary from simple inflammatory reactive lesion to a malignant condition.Therefore lymphadenopathy requires further evaluation. FNAC has been a suitable investigation to rule out malignancies and to confirm reactive or infective pathology.2,3 The use of fine needle aspiration cytology (FNAC) in the investigation of lymphadenopathy has become an acceptable and widely practiced minimally invasive technique, which is safe, relatively painless, simple and rapid. FNAC is highly cost effective and accurate as a first line investigative technique. With the recent advances in ultrasound and CT scan technologies, focal lesions can be aspirated using this procedures. 4 Fine needle aspiration cytology (FNAC) has emerged as an advanced diagnostic tool to differentiate reactive hyperplasia/inflammatory conditions, granulomatous disorders and lymphomas. This diagnostic modality has gained considerable importance in the management of patients with lymphadenopathy over several years. We are reporting histopathological correlation of 200 cases of lymphadenopathy with FNAC. ABSTRACTBackground: Lymphadenopathy is very common presenting symptoms. Fine needle aspiration cytology (FNAC) is used to evaluate the nature of the lesion. Etiology of lymphadenopathy in head and neck region vary from benign reactive hyperplasia to tubercular granulomatous lesion to malignancy. The aim of present study was to evaluate the sensitivity, specificity and predictive value in tuberculosis and metastatic carcinoma. Methods: A total of 80 patients out of 200 patients who underwent FNAC were evaluated by histopathological examination for correlation. Aspiration smears and histopathological slides were evaluated and results were calculated for sensitivity, specificity and predictive value. Results: Reactive lymphadenitis was seen in 40 patients followed by tubercular granulomatous lymphadenitis in 20 patients and malignant lesions in 20 patients. Histology revealed 18 patients of tubercular lymphadenitis, 43 of reactive changes, 12 of metastasis in lymph nodes and 7 of lymphomas. Correlating the findings, we could achieve 100% sensitivity and 96.7% specificity for tubercular lymphadenopathy and for metastatic it was 98.5% and 100% respectively. Conclusions: We have found FNAC a satisfactory tool in the diagnosis of tubercular and malignant lymphadenopathy. FNAC used in conjunction with clinical findings, radiological and laboratory investigations can be a cost effective method for the diagnosis of lymphadenopathy.

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“…In our study of 67 tumors in the parapharyngeal space, exact classifi cation of the lesion was possible in 92.5% cases with no false positive report or complication. The diagnostic accuracy of various head and neck tumors by cytology including FNAC varies from 80-95% by various authors [9][10][11][12][13][14][15][16][17].…”

Section: Discussionmentioning

confidence: 99%

Peroral fine needle aspiration cytology of parapharyngeal tumors: a study of 67 cases

Chatterjee¹,

Mondal²

2009

Indian J Otolaryngol Head Neck Surg

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Peroral fi ne needle aspiration cytology (FNAC) was carried out to diagnose parapharyngeal tumors in 67 patients from January 2000 to January 2008. The infl ammatory lesions were excluded in the present study. The age of patients ranged from 6 years to 72 years. Analysis of results showed 35 benign tumors and 32 malignant neoplasms. Correlation with histopathology showed a diagnostic accuracy of 92.5% with no false positive report. No complication was encountered in the present study. FNAC can replace incisional biopsy which may be hazardous in this area. Immediate treatment can be planned based on the FNAC report. Such a large series of parapharyngeal tumors diagnosed by FNAC has hardly been reported in India.

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Aspiration cytology of head and neck masses

Cited by 45 publications

References 6 publications

Evaluation of fine needle aspiration biopsy as a diagnostic tool in pediatric head and neck lesions

Evaluation of fine needle aspiration biopsy as a diagnostic tool in pediatric head and neck lesions

Correlation of fine needle aspiration cytology lymph node with histopathological diagnosis

Peroral fine needle aspiration cytology of parapharyngeal tumors: a study of 67 cases

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