Aspiration cytology of Wilms' tumor: Correlation of cytologic and histologic features

Abstract

We examined the cytomorphologic features of fine-needle aspiration biopsy (FNAB) specimens from 23 Wilms' tumor patients. The findings were correlated with histopathologic patterns from these tumors. The study revealed a close resemblance between the cytologic and histopathologic appearance of various cellular elements in Wilms' tumors. The major cellular patterns seen in Wilms' tumor include blastemal cells, blastemal cells with epithelial differentiation, blastemal cells with tubular differentiation, and stromal elements. It is hoped that recognition of these cellular components in aspiration smears will be helpful in establishing an FNAB diagnosis of Wilms' tumor.

Fine Needle Aspiration Cytology of Clear Cell Sarcoma of the Kidney

“…2,6 In addition to these, differentiated stromal cells, such as muscle, may also be noted. The cytodiagnosis of pure blastemal variant of Wilms' …”

Small Round Cell Tumors of the Abdomen and Thorax

“…1 A review of the literature shows that the various cytomorphologic features that could be useful in the diagnosis of SRCT are rosettes and filamentous/fibrillar matrix in neuroblastoma, tubule formation in nephroblastoma, tadpole cells in rhabdomyosarcoma and neuroblastoma, PAS-positive inclusions in Ewing's sarcoma, nuclear grooves in histiocytosis X, noncohesive cells in lymphoma and histiocytosis X, lymphoglandular bodies in NHL, and nuclear molding and PBIs in small cell anaplastic carcinoma. 2,3,12,21,25,31,34,38 Most of these studies were based on either assessment of multiple cytomorphologic characteristics in a specific subtype of SRCT 2,3,24,34 or a single cytomorphologic feature in various SRCTs. 25,38 In the present study an attempt was made to critically assess the role of 12 cytomorphologic features in the diagnosis of specif- The rosettes observed in neuroblastoma and ganglioneuroblastoma have been referred to as "Homer-Wright" rosettes 20,24,34 or pseudorosettes.…”

Fetal rhabdomyomatous nephroblastoma: Diagnosis by fine-needle aspiration cytology?a case report

“…9 Several papers have addressed the subject of recognizing the different types of renal tumors to be found in infants and children, using the fine-needle aspiration cytology (FNAC) approach. [11][12][13][14][15][16][17][18][19][20][21][22] However, we have not been able to find any report referring specifically to FRN. Since adequate diagnosis may prove useful for treatment planning, we are reporting on the present case.…”