Aspirin curcumin ester loaded biomimetic nanodrug improves cognitive deficits in a mouse model of Alzheimer's disease by regulating M1/M2 microglial polarization

Li, Ze; Song, Zhenyan; He, Chunnian; Fan, Jialong; Yu, Wei; Miao, Yuqing; Li, Ping; Luo, Rongsiqing; Zhou, Jin‐Yong; Xu, Sijie; Liu, Bin; Cheng, Shaowu

doi:10.1016/j.mtadv.2022.100321

Cited by 4 publications

(2 citation statements)

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“…Hybrid membrane-coated biomimetic nanocarriers are prepared by fuzing two different cell membranes and combining the functions and biomarker activities of both cell types ( Table 6 ) (Berta Esteban-Fernández et al., 2018 ; Raza et al., 2021 ; Li et al., 2022d ). In a recent study, murine J774A.1 cells and head and neck tumor HN12 cells were used to design a composite cell membrane-camouflaged biomimetic nanoplatform (He et al., 2018 ).…”

Section: Cell Membrane-based Biomimetic Nanoparticles For Natural Pro...mentioning

confidence: 99%

Advances in cell membrane-based biomimetic nanodelivery systems for natural products

Zhang,

et al. 2024

Drug Delivery

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Section: Cell Membrane-based Biomimetic Nanoparticles For Natural Pro...mentioning

confidence: 99%

Advances in cell membrane-based biomimetic nanodelivery systems for natural products

Zhang,

et al. 2024

Drug Delivery

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“…The group treated with MCAGP NPs was compared to other groups and the subjects had shorter escape latencies and swimming speeds and crossed over the platform in the Morris Waster maze test. 136 Han and colleagues developed a genistein (GS) loaded solid lipid nanoparticle (SLN) formulation coated with a macrophage membrane (MA). The macrophage membrane coating enabled the escape of nanocarrier from the reticuloendothelial system compounds.…”

Section: The Use Of Nanoscale Drug Delivery Systems In the Treatment ...mentioning

confidence: 99%

Current Overview on the Use of Nanosized Drug Delivery Systems in the Treatment of Neurodegenerative Diseases

Ozceylan,

Sezgin-Bayindir

2024

ACS Omega

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Neurodegenerative diseases, encompassing conditions such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis, prion disease, and Huntington's disease, present a growing health concern as human life expectancy increases. Despite this, effective treatments to halt disease progression remain elusive due to various factors, including challenges in drug delivery across physiological barriers like the blood−brain barrier and patient compliance issues leading to treatment discontinuation. In response, innovative treatment approaches leveraging noninvasive techniques with higher patient compliance are emerging as promising alternatives. This Review aims to synthesize current treatment options and the challenges encountered in managing neurodegenerative diseases, while also exploring innovative treatment modalities. Specifically, noninvasive strategies such as intranasal administration and nanosized drug delivery systems are gaining prominence for their potential to enhance treatment efficacy and patient adherence. Nanosized drug delivery systems, including liposomes, polymeric micelles, and nanoparticles, are evaluated within the context of outstanding studies. The advantages and disadvantages of these approaches are discussed, providing insights into their therapeutic potential and limitations. Through this comprehensive examination, this Review contributes to the ongoing discourse surrounding the development of effective treatments for neurodegenerative diseases.

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Curcumin Nanoformulations in Neurodegenerative Diseases

Kakkar,

Kumari,

Kaur

et al. 2023

Curcumin and Neurodegenerative Diseases

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Aspirin curcumin ester loaded biomimetic nanodrug improves cognitive deficits in a mouse model of Alzheimer's disease by regulating M1/M2 microglial polarization

Cited by 4 publications

References 50 publications

Advances in cell membrane-based biomimetic nanodelivery systems for natural products

Advances in cell membrane-based biomimetic nanodelivery systems for natural products

Current Overview on the Use of Nanosized Drug Delivery Systems in the Treatment of Neurodegenerative Diseases

Curcumin Nanoformulations in Neurodegenerative Diseases

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