Aspirin induced fixed drug eruptions: a case report

Bhosale, Rama R.; Bodke, Pradeep S.; Ghadlinge, Manik; Chandane, Rakhamaji D.

doi:10.5455/2319-2003.ijbcp20130319

Cited by 3 publications

(4 citation statements)

References 3 publications

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“…Most of the earlier reported cases had fixed drug eruption associated with the administration of diclofenac. [4] Anaphylactic reaction associated with IV diclofenac in other reported cases were associated with pulmonary embolism, and fatal cardiovascular outcomes, myocardial infarction, and shock,[5] unlike in our case, no such event happened. The health-care professionals (HCPs) should be aware of such serious reaction, so that early diagnosis and treatment can prevent further complications.…”

Section: Discussionmentioning

confidence: 44%

Anaphylactic reaction induced by intravenous diclofenac: A case report

2019

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Among the immune-mediated reactions, anaphylaxis is the most severe form. As a postoperative analgesia, diclofenac sodium, and nonsteroidal anti-inflammatory drug is commonly used. Intravenous (IV) diclofenac sodium-induced anaphylaxis is very rare. We are presenting a case of IV diclofenac-induced anaphylactic reaction, occurred during the surgery in a female patient of 21 years of age. The sign and symptoms of the reaction resembled an anaphylactic reaction. Temporal relationship with IV diclofenac administration and development of the clinical features of the reaction found to be probable. The health-care professionals should be aware of such rare and serious reactions so that it can be diagnosed and treated early. The clinical importance associated with the case encouraged us to report this rare complication of IV diclofenac.

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Section: Discussionmentioning

confidence: 44%

Anaphylactic reaction induced by intravenous diclofenac: A case report

2019

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“…[3] Even though, the pathogenesis of FDE is not known, certain serum factors, antibodies, and cell mediated immunity have been attributed as causative factors. FDE is a delayed type hypersensitivity reaction mediated by CD 8+ T-cells.…”

Section: Discussionmentioning

confidence: 99%

“…A large number of drugs have been reported to elicit FDEs such as trimethoprim-sulfamethoxazole, tetracyclines, penicillin, erythromycin, nonsteroidal antiinflammatory drugs, barbiturates, valproate, phenytoin, phenolphthalein, and nitroimidazoles. [ 3 ] Even though, the pathogenesis of FDE is not known, certain serum factors, antibodies, and cell mediated immunity have been attributed as causative factors. FDE is a delayed type hypersensitivity reaction mediated by CD 8+ T-cells.…”

Section: Discussionmentioning

confidence: 99%

Fixed drug eruptions caused by cross-reactive quinolones

Kameswari¹,

Selvaraj²,

Adhimoolam³

2014

J Basic Clin Pharma

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“…Fixed drug eruptions (FDE) are common dermatological adverse drug reactions which are commonly caused by antimicrobials, anticonvulsants and non-steroidal anti-inflammatory drugs. It is a clinical condition occurring in the same site/sites each time when the drug is administered [4].…”

Section: Introductionmentioning

confidence: 99%

Diclofenac Induced Fixed Drug Eruption

Prabhu¹

2016

JPCR

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Fixed drug eruptions (FDE) are common dermatological adverse drug reactions which are commonly caused by antimicrobials, anticonvulsants and non-steroidal anti-inflammatory drugs. It is a clinical condition occurring in the same site/sites each time when the drug is administered. Here we present a case of diclofenac induced fixed drug eruption with a Naranjo scoring of 6 (Probable). The patient recovered after stopping diclofenac. This projects the importance of ADR monitoring which is a part of Pharmacovigilance Programme of India (PvPI).

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Aspirin induced fixed drug eruptions: a case report

Cited by 3 publications

References 3 publications

Anaphylactic reaction induced by intravenous diclofenac: A case report

Anaphylactic reaction induced by intravenous diclofenac: A case report

Fixed drug eruptions caused by cross-reactive quinolones

Diclofenac Induced Fixed Drug Eruption

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