Aspirin is an enhancing factor for food‐dependent exercise‐induced anaphylaxis in children

Novel insights regarding anaphylaxis in children ‐ With a focus on prevalence, diagnosis, and treatment

“…Provocation tests are considered positive when patients have allergic symptoms after consumption of specific food allergen and exercise. [23][24][25][26][27][28][29][30] The Japanese Food Allergy Guideline recommends a provocation test for patients with suspected FDEIA. 20 24,29,31 The causative food for FDEIA based on the provocation test is often wheat in adults and varies in children.…”

“…In most children, the food that caused FDEIA, as confirmed by a provocation test, was wheat, followed by shrimp and fruits (Table 1). 23,29 According provocation tests were reported in Italy. Of 67 patients estimated to be susceptible to causative foods, the causative food was tomatoes in 25 patients and wheat in 8 patients.…”

“…The Japanese Food Allergy Guideline recommends a provocation test for patients with suspected FDEIA 20 . Table 1 summarizes the methods of provocation tests and presents the causative foods for patients with FDEIA 23,25–29 . Patients start exercising 60 minutes after eating food, and if the amount of exercise is inadequate, allergic symptoms are sometimes not induced.…”

“…Provocation tests are considered positive when patients have allergic symptoms after consumption of specific food allergen and exercise 23–30 . The Japanese Food Allergy Guideline recommends a provocation test for patients with suspected FDEIA 20 .…”

Developments in the field of allergy in 2017 through the eyes of Clinical and Experimental Allergy

“…Motomura and colleagues have examined the effect of aspirin on challenge tests for food-dependent exercise induced anaphylaxis. 29 Twenty-six children had positive challenges. In half the combination of food and exercise induced allergic symptoms.…”