2016
DOI: 10.1021/acs.orglett.6b00336
|View full text |Cite
|
Sign up to set email alerts
|

Aspterpenacids A and B, Two Sesterterpenoids from a Mangrove Endophytic Fungus Aspergillus terreus H010

Abstract: Two new sesterterpenoids, aspterpenacids A (1) and B (2), with an unusual carbon skeleton of a 5/3/7/6/5 ring system were isolated from the mangrove endophytic fungus Aspergillus terreus H010. Their structures were elucidated on the basis of spectroscopic methods, single-crystal X-ray diffraction analysis, and electronic circular dichroism calculations. A biogenetic pathway for 1 and 2 is proposed. Both 1 and 2 showed no significant antibacterial activity or cytotoxicity at 50 μM.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3

Citation Types

0
59
0

Year Published

2016
2016
2020
2020

Publication Types

Select...
10

Relationship

3
7

Authors

Journals

citations
Cited by 100 publications
(59 citation statements)
references
References 17 publications
0
59
0
Order By: Relevance
“…In the past decades, our research group had been focusing on the exploration of new bioactive metabolites from mangrove endophytic fungi collected from the South China Sea [6,7,8,9,10,11,12,13]. The EtOAc extract of the fermentation of a mangrove endophytic fungus, Penicillium sp.…”
Section: Introductionmentioning
confidence: 99%
“…In the past decades, our research group had been focusing on the exploration of new bioactive metabolites from mangrove endophytic fungi collected from the South China Sea [6,7,8,9,10,11,12,13]. The EtOAc extract of the fermentation of a mangrove endophytic fungus, Penicillium sp.…”
Section: Introductionmentioning
confidence: 99%
“…In the last decade, our research group has been devoted to finding novel bioactive compounds from mangrove endophytic fungi derived from the South China Sea [1015]. In a previous study, a chemical investigation of the endophytic fungal strain Aspergillus sp.…”
Section: Introductionmentioning
confidence: 99%
“…Aspergillus terreus is a filamentous fungus distribute widely in natural world, and from the culture broth of it, a variety of natural products have been isolated, such as alkaloids, 1,2 meroterpenoids, 3,4 sesterterpenoids, 5 lignans, 2,6,7 , and so on. The most famous metabolite from A. terreus is lovastatin (named as mevinolin at first), which is an important HMG-CoA reductase inhibitor clinically used.…”
Section: Introductionmentioning
confidence: 99%