The Atlantic Meridional Overturning Circulation (AMOC) variability is suggested to be incoherent between the subpolar and subtropical gyres in the Atlantic on interannual and even decadal time scales, questioning the representativeness of AMOC variability at a single latitude in modern observation and paleoreconstruction. Paleoreconstructions of the Florida Current transport suggest that Florida Current variability is associated with the AMOC on the millennial time scale, but the Rapid Climate Change (RAPID) mooring array suggests a weak correlation between the Florida Current and the AMOC. In this study, we investigate the meridional coherence of AMOC variability and the relationship between the Florida Current variability and the AMOC variability on different time scales in a transient 20,000‐year simulation. We find that with the increase of time scales, the meridional coherence of the AMOC increases. On decadal and longer time scales, the coherent subtropical and subpolar AMOC is caused by the coherent buoyancy forcing in the subpolar gyre. Also, the Florida Current transport is highly correlated with AMOC variability on decadal and longer time scales, suggesting that observations of the Florida Current can be used to indicate AMOC variability on long time scales.