Phu Quoc Island, a popular coastal destination in Vietnam, faces increasing vulnerability to climate change, particularly sea level rise. This study delves into the landscape of sea level rise vulnerability across diverse sectors and geographies within Phu Quoc. The study examines various sectors and geographic locales, shedding light on the impacts under the 50 cm sea level rise scenario. Coastal regions, notably Duong Dong and An Thoi, stand as epicenters of vulnerability due to their high population density, extensive infrastructure, and pivotal economic sectors. Duong Dong, envisioned as a tourism hub, exhibits the highest vulnerability to climate change, exacerbated by potential issues in natural forest land planning and urban drainage infrastructure. The Agriculture-Fisheries sector faces substantial challenges, including the loss of arable land and declining catch volumes, underscoring the need for enhanced adaptive capacity. The study provides valuable insights for stakeholders, emphasizing the urgency of adaptive measures to mitigate sea level rise impacts in Phu Quoc.