Assessment of a computer-based treatment for older amblyopes: the Glasgow Pilot Study

Cleary, Marie; Moody, Amy; Buchanan, Alice M.; Stewart, Hannah; Dutton, Gordon N.

doi:10.1038/sj.eye.6702977

Cited by 69 publications

(55 citation statements)

References 36 publications

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“…More recently, attempts have been published to enhance the outcome of amblyopia treatment in older children by means of specific training procedures [33][34][35]. Their potential compared to the established treatment has still to be verified in large groups of patients.…”

Section: Future Prospectsmentioning

confidence: 97%

Electronic monitoring of occlusion treatment for amblyopia in patients aged 7 to 16 years

Fronius

Bachert

Lüchtenberg

2009

Graefes Arch Clin Exp Ophthalmol

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This study presents for the first time objective treatment and dose response data in amblyopic patients beyond the "classical" treatment age. Electronic monitoring of occlusion and considerable amounts of patching were shown to be feasible. The acuity results indicate that there is a potential for improvement, yet treatment seemed to be less efficient than shown by previous studies in younger patients. Continuation of this research may advance the discussion about age-dependent evidence-based amblyopia treatment, about preschool screening for amblyopia and about plasticity of the visual system.

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Section: Future Prospectsmentioning

confidence: 97%

Electronic monitoring of occlusion treatment for amblyopia in patients aged 7 to 16 years

Fronius

Bachert

Lüchtenberg

2009

Graefes Arch Clin Exp Ophthalmol

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“…For some patients, I-BiT™ treatment alone was sufficient to improve vision to a satisfactory level at which no further treatment was required (19). In other patients, residual amblyopia remained, and VA was further improved with such traditional amblyopia treatment as occlusion patching (23).…”

Section: Clinical Case Studiesmentioning

confidence: 98%

Virtual reality for interactive binocular treatment of amblyopia

Waddingham¹,

Cobb²,

Eastgate³

et al. 2006

International Journal on Disability and Human Development

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Amblyopia, or 'lazy eye', is currently treated by wearing an adhesive patch over the non-amblyopic eye for several hours per day, over a period of many months. Non-compliance with patch wearing is a significant problem. Our multi-displinary team involved clinicians and technologists to investigate the application of virtual reality technology in a novel way. We devised a binocular treatment system in which children watch a video clip of a cartoon on a virtual TV screen, followed by playing an interactive computer game to improve their vision. So far the system has been used to treat 39 children, of whom 87% have shown some improvement in vision. Vision improvement tended to occur within the first three to four treatment sessions. This paper describes research development of the I-BiT™ system. We present a summary of results from the clinical case studies conducted to date and discuss the implications of these findings with regard to future treatment of amblyopia. INTRODUCTIONAmblyopia, or 'lazy eye', is reduced corrected visual acuity that exists in the absence of any detectable organic disease. Amblyopia can be the result of a squint (strabismic amblyopia), in which both eyes are not straight, a difference of the refractive state of each eye (anisometropic amblyopia), or the result of both squint and refractive inequality (mixed amblyopia, combined anisometropic and strabismic amblyopia), in which there is a squint as well as a stronger corrective glasses lens for one eye. This condition affects 2% to 5% of the population (1,2) and is currently treated by wearing an adhesive patch over the non-amblyopic eye for several hours per day, over a period of many months (3). Although this form of occlusion therapy is successful, the success rates are variable (4) and non-compliance with patch wearing is a problem that can result in unsuccessful treatment (5).

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“…Cleary, Moody, Buchanan, Stewart, and Dutton (2009) tested this system in 12 amblyopic children who did not comply or respond to occlusion. Specifically, in each of 8 sessions, the children viewed a 20-min video clip with the “detail” viewed by the amblyopic eye and the surrounding frame by the fellow eye, and spent 5 min playing an interactive videogame with the detail of the visual scene split between the two eyes.…”

Section: Can Stereopsis Be Recovered In Children and Adults With Amentioning

confidence: 99%

Stereopsis and amblyopia: A mini-review

2015

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Amblyopia is a neuro-developmental disorder of the visual cortex that arises from abnormal visual experience early in life. Amblyopia is clinically important because it is a major cause of vision loss in infants and young children. Amblyopia is also of basic interest because it reflects the neural impairment that occurs when normal visual development is disrupted. Amblyopia provides an ideal model for understanding when and how brain plasticity may be harnessed for recovery of function. Over the past two decades there has been a rekindling of interest in developing more effective methods for treating amblyopia, and for extending the treatment beyond the critical period, as exemplified by new clinical trials and new basic research studies. The focus of this review is on stereopsis and its potential for recovery. Impaired stereoscopic depth perception is the most common deficit associated with amblyopia under ordinary (binocular) viewing conditions (Webber & Wood, 2005). Our review of the extant literature suggests that this impairment may have a substantial impact on visuomotor tasks, difficulties in playing sports in children and locomoting safely in older adults. Furthermore, impaired stereopsis may also limit career options for amblyopes. Finally, stereopsis is more impacted in strabismic than in anisometropic amblyopia. Our review of the various approaches to treating amblyopia (patching, perceptual learning, videogames) suggests that there are several promising new approaches to recovering stereopsis in both anisometropic and strabismic amblyopes. However, recovery of stereoacuity may require more active treatment in strabismic than in anisometropic amblyopia. Individuals with strabismic amblyopia have a very low probability of improvement with monocular training; however they fare better with dichoptic training than with monocular training, and even better with direct stereo training.

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Assessment of a computer-based treatment for older amblyopes: the Glasgow Pilot Study

Cited by 69 publications

References 36 publications

Electronic monitoring of occlusion treatment for amblyopia in patients aged 7 to 16 years

Electronic monitoring of occlusion treatment for amblyopia in patients aged 7 to 16 years

Virtual reality for interactive binocular treatment of amblyopia

Stereopsis and amblyopia: A mini-review

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