2017
DOI: 10.1002/jmri.25605
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Assessment of acute thermal damage volumes in muscle using magnetization‐prepared 3D T2‐weighted imaging following MRI‐guided high‐intensity focused ultrasound therapy

Abstract: Purpose To evaluate magnetization-prepared 3D T2-weighted MR imaging measurements of acute tissue changes produced during ablative MR-HIFU exposures. Methods A clinical MR-HIFU system (3T) was used to generate thermal lesions (n=24) in the skeletal muscles of three pigs. T1-weighted, 2D T2-weighted, and magnetization-prepared 3D T2-weighted sequences were acquired before and after therapy to evaluate tissue changes following ablation. Tissues were harvested shortly after imaging, fixed in formalin, and gross… Show more

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Cited by 7 publications
(19 citation statements)
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“…Furthermore, there was good agreement in Bland–Altman plots. Staruch et al reported similar correlations for lesion size in pig muscle measured between T 2 W and contrast‐enhanced T 1 W images, following MRI‐guided high‐intensity focused ultrasound therapy …”
Section: Discussionmentioning
confidence: 75%
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“…Furthermore, there was good agreement in Bland–Altman plots. Staruch et al reported similar correlations for lesion size in pig muscle measured between T 2 W and contrast‐enhanced T 1 W images, following MRI‐guided high‐intensity focused ultrasound therapy …”
Section: Discussionmentioning
confidence: 75%
“…In our study, the laser beam activation time at each location varied from 60 sec to 120 sec. This could produce variations in the tissue damage . These variations were not considered in the present study.…”
Section: Discussionmentioning
confidence: 99%
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