Assessment of anti-Mullerian hormone level in reproductive age group women with diabetes mellitus type one

Khafaji, Masar Mahdi Al; Al-Taee, Hanan A.; Al-Shaikh, Suhaila Fadhil

doi:10.1016/j.mefs.2017.04.004

Cited by 4 publications

(2 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The samples were also taken within a narrow window of 20 days for the 1st trimester measurement and 34 days for the 2nd trimester measurement, therefore limiting the potential variability originating from differences in gestational age. The study population had limited heterogeneity as participants with PCOS or diabetes were excluded from this study, to make the data less susceptible to the effects of extreme outliers (Al Khafaji et al, 2017, Kim et al, 2016, Bhattacharya et al, 2022, Teede et al, 2019, Verdiesen et al, 2021. As such, these results cannot be generalised to women with PCOS or diabetes.…”

Section: Discussionmentioning

confidence: 99%

Serum anti-Müllerian hormone (AMH) concentration during pregnancy: a longitudinal study

McCredie

McShane

et al. 2023

Reproduction and Fertility

View full text Add to dashboard Cite

A prospective longitudinal cohort study aimed to longitudinally examine the kinetics of Anti-müllerian hormone (AMH) during the first two trimesters of pregnancy. Pregnant women with stored 1st trimester serum samples were recruited at 24-28 weeks gestation during their gestational diabetes testing, where they provided an additional serum sample. The samples were analysed for AMH, oestradiol and progesterone concentrations. A decrease in serum AMH was observed in 40 out of 45 (88.9%) (95% CI 75.9% to 96.3%) of the participants in this study. The median serum AMH concentration was 10.9 pmol/L in the 1st trimester and 6.5 pmol/L during the 2nd trimester, with a significantly different distribution of the values between the 1st and the 2nd trimester AMH samples (p<0.001). The median percentage of AMH difference of -39.8%. This study demonstrated a significant decrease in serum AMH levels from the 1st to the 2nd trimester of pregnancy. The absolute decrease in AMH levels seems to be positively associated with 1st trimester AMH levels, whereas the percentage of AMH difference is not. Further studies are required to elucidate the potential physiological mechanisms of this finding.

show abstract

Section: Discussionmentioning

confidence: 99%

Serum anti-Müllerian hormone (AMH) concentration during pregnancy: a longitudinal study

McCredie

McShane

et al. 2023

Reproduction and Fertility

View full text Add to dashboard Cite

show abstract

“…Совсем недавно до выхода печатной версии статьи онлайн опубликованы результаты исследования Al Khafajia и соавт. [12], в рамках которого анализировались параметры овариального резерва у 60 молодых больных СД1 и 80 здоровых молодых женщин (средний возраст 24,87±8,47 лет и 25,91±8,29 лет соответственно). Авторы показали значимо меньшие уровни АМГ (2,82±1,27 нг/мл и 3,79±1,91 нг/мл) и более высокие уровни HbA 1с (8,73±2,8% и 4,82±0,39%) в группе больных СД1 по сравнению со здоровыми женщинами соответственно (p<0,00 для обоих сравнений).…”

Section: Discussionunclassified

Ovarian reserve in reproductive age women with type 1 diabetes

et al. 2018

View full text Add to dashboard Cite

Background: Premature aging are frequently observed among individuals with type 1 diabetes. Decrease of ovarian reserve may be one of the characteristics of such process. Aims: To evaluate the ovarian reserve function in female patients of reproductive age with type 1 diabetes in comparison with healthy women. Materials and methods: This study evaluated 224 Caucasian women, age 1837 years with type 1 diabetes and 230 healthy women of comparable age. Serum concentrations of anti-Mullerian hormone (AMH), inhibin B, follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol, progesterone and testosterone were compared on the 23 day of menstrual cycle as ovarian volume and antral follicle count (AFC). In addition, glycated hemoglobin level (HbA1c%) was evaluated. Results: We reveal statistically significant difference in following parameters in diabetic women in comparison with healthy women: AMH, AFC. But even in diabetic patients parameters remained within reference ranges. There was a pronounced negative relationship between the levels of HbA1c% and AMG. Conclusions: Ovarian reserve function parameters decrease in young women with type 1 diabetes in comparison with healthy women, but ovarian reserve parameters are in normal reference range. These findings are important in pregnancy planning consulting by gynecologists and endocrinologists. We must recommend to women with type 1 diabetes more early planning of natural pregnancy for treatment with reproductive technology in cases of prolog absence of nature pregnancy.

show abstract

Analysis of genomic and post-genomic factors influenced to the ovarian reserve in reproductive age womenwith type 1 diabetes

Grigoryan¹,

Krasnovskaya²,

Михеев³

et al. 2019

Probl. reprod.

View full text Add to dashboard Cite

Assessment of anti-Mullerian hormone level in reproductive age group women with diabetes mellitus type one

Cited by 4 publications

References 36 publications

Serum anti-Müllerian hormone (AMH) concentration during pregnancy: a longitudinal study

Serum anti-Müllerian hormone (AMH) concentration during pregnancy: a longitudinal study

Ovarian reserve in reproductive age women with type 1 diabetes

Analysis of genomic and post-genomic factors influenced to the ovarian reserve in reproductive age womenwith type 1 diabetes

Contact Info

Product

Resources

About