Assessment of breast mass morphology with diffusion‐weighted MRI: Beyond apparent diffusion coefficient

Kul, Sibel; Metin, Yavuz; Kul, Musa; Metin, Nurgül Orhan; Eyüboğlu, İlker; Özdemir, Oğuz

doi:10.1002/jmri.26175

Cited by 23 publications

(19 citation statements)

References 36 publications

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“…On the other hand, there is a growing interest in the development of contrast-agent free protocols by using the acquisition of diffusion-weighted images (DWI) and their respective Apparent diffusion coefficient (ADC) maps [69] , [70] , [49] , [71] , [72] , [54] , especially because gadolinium deposition in the brain has been described recently [73] . Bickelhaupt et al [69] , [70] proposed to use diffusion-weighted imaging with background suppression (DWIBS) for defining an ABB-MRI protocol and clarify mammogram based screening findings.…”

Section: Resultsmentioning

confidence: 99%

“…Chen et al [49] showed that adding the diffusion to a protocol based on the first post-contrast sequence and MIP, significantly improves the performance of the protocol. Likewise, in 2018, Kul et al [72] conducted a study that seeks to establish the viability of using the acquisition of diffusion-weighted images and ADC map for describing the cellularity of masses detected in the breasts and to establish the contribution of this evaluation for its characterization. From the reported results, the diffusion images showed a high to moderate concordance during breast masses description respect to dynamic contrast-enhanced (DCE) study.…”

Section: Resultsmentioning

confidence: 99%

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Abbreviated magnetic resonance imaging in breast cancer: A systematic review of literature

Hernández

Osorio

Florez

et al. 2021

European Journal of Radiology Open

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Background : magnetic resonance imaging (MRI) has been increasingly used to study breast cancer for screening high-risk cases, pre-operative staging, and problem-solving because of its high sensitivity. However, its cost-effectiveness is still debated. Thus, the concept of abbreviated MRI (ABB-MRI) protocols was proposed as a possible solution for reducing MRI costs Purpose : to investigate the role of the abbreviated MRI protocols in detecting and staging breast cancer Methods : a systematic search of the literature was carried out in the bibliographic databases: Scopus, PubMed, Medline, and Science Direct. Results : forty-one articles were included, which described results of the assessment of fifty-three abbreviated protocols for screening, staging, recurrence assessing, and problem-solving or clarification. Conclusions : the use of ABB-MRI protocols allows reducing the acquisition and reading times, maintaining a high concordance with the final interpretation, in comparison to a complete protocol. However, larger prospective and multicentre trials are necessary to validate the performance in specific clinical environments

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Abbreviated magnetic resonance imaging in breast cancer: A systematic review of literature

Hernández

Osorio

Florez

et al. 2021

European Journal of Radiology Open

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“…A further 103 studies were excluded for the study type (not articles), 40 studies were excluded for the language, and 111 studies were excluded for failure to meet the eligibility criteria after carefully reading the full text: failure to extract the number of true positives, false negatives, false negatives, and true negatives; no mp-MRI to diagnose breast cancer; and did not use 1.5-T or 3.0-T MRI machines. Finally, 22 studies were included in the meta-analysis (2–4,8–12,14–17,29–38).…”

Section: Resultsmentioning

confidence: 99%

Accuracy of multiparametric MRI in distinguishing the breast malignant lesions from benign lesions: a meta-analysis

et al. 2020

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Background The sensitivity of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for detecting breast cancer was high and the specificity was relatively low. However, diffusion-weighted imaging (DWI) has a high specificity in the diagnosis of malignant lesions. Purpose To evaluate the accuracy of the multiparametric MRI (mp-MRI) in distinguishing the breast malignant lesions from the benign lesions. Material and Methods A comprehensive search of the PubMed, Embase, and Cochrane Library electronic databases was conducted up to March 2020. Data were analyzed for the following indexes: pooled sensitivity and specificity; positive likelihood ratio; negative likelihood ratio; diagnostic odds ratio; and the area under the curve. Results A total of 2356 patients with 1604 malignant and 967 benign breast lesions were included from 22 studies. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio, and area under the curve for mp-MRI were 0.93, 0.85, 6.3, 0.08, 81, and 0.96, respectively. The pooled sensitivity, specificity, and area under the curve for DCE-MRI alone were 0.95, 0.71, and 0.92, respectively. The pooled sensitivity, specificity, and area under the curve for DWI alone were 0.88, 0.84, and 0.93, respectively. Conclusion The mp-MRI did not improve the sensitivity but increased the specificity for the diagnosis of breast malignant lesions.

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“…While most previous papers focused on ADC values obtained from DWI, there are a few reports concerning morphological assessment of breast lesions using ss-EPI with an HR-DWI Using rs-EPI for Breast 1.5T MRI scanner. 30,31 Another report showed the additive diagnostic value in analysis of breast lesion using rs-EPI (voxel size: 2.1 × 1.8 × 4.0 mm 3 ) with a 3T MRI scanner. 23 These previous reports pointed out the value of less-distorted DWI.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Malignant Breast Lesions Using High-resolution Readout-segmented Diffusion-weighted Echo-planar Imaging: Comparison with Pathology

Kishimoto

Kataoka

Iima

et al. 2021

MRMS

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We aimed to investigate the performance of high resolution-diffusion-weighted imaging (HR-DWI) using readout-segmented echo-planar imaging in visualizing malignant breast lesions and evaluating their extent, using pathology as a reference.Methods: This retrospective study included patients who underwent HR-DWI with surgically confirmed malignant breast lesions. Two radiologists blinded to the final diagnosis evaluated HR-DWI independently and identified the lesions, measuring their maximum diameters. Another radiologist confirmed if those lesions were identical to the pathology. The maximum diameters of the lesions between HR-DWI and pathology were compared, and their correlations were calculated using Spearman's correlation coefficient. Apparent diffusion coefficient (ADC) values of the lesions were measured.Results: Ninety-five mass/64 non-mass lesions were pathologically confirmed in 104 females. Both radiologists detected the same 93 mass lesions (97.9%). Spearman's correlation coefficient for mass lesions were 0.89 and 0.90 (P < 0.0001 and 0001) for the two radiologists, respectively. The size differences within 10 mm were 90.3% (84/93) and 94.6% (88/93) respectively. One radiologist detected 35 non-mass lesions (54.7%) and another radiologist detected 32 non-mass lesions (50.0%), of which 28 lesions were confirmed as identical. Spearman's correlation coefficient for non-mass lesions were 0.59 and 0.22 (P = 0.0002 and 0.22), respectively. The mean ADC value of mass lesions and non-mass lesions were 0.80 and 0.89 × 10 −3 mm 2 /s, respectively. Conclusion:Using HR-DWI, malignant mass lesions were depicted with excellent agreement with the pathological evaluation. Approximately half of the non-mass lesions could not be identified, suggesting a current limitation of HR-DWI.

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Assessment of breast mass morphology with diffusion‐weighted MRI: Beyond apparent diffusion coefficient

Abstract: 3 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018;48:1668-1677.

Cited by 23 publications

References 36 publications

Abbreviated magnetic resonance imaging in breast cancer: A systematic review of literature

Abbreviated magnetic resonance imaging in breast cancer: A systematic review of literature

Accuracy of multiparametric MRI in distinguishing the breast malignant lesions from benign lesions: a meta-analysis

Evaluation of Malignant Breast Lesions Using High-resolution Readout-segmented Diffusion-weighted Echo-planar Imaging: Comparison with Pathology

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