Assessment of Central Corneal Thickness in Adults With Indications For Kidney Transplantation and Commenting On Some Related Factors

Abstract

Objectives Central corneal thickness (CCT) is an important biological indicator of eyeball affecting intraocular pressure, which plays a vital role in glaucoma pathology. This study investigated the central corneal thickness in renal failure subjects with indications for kidney transplantation and commented on some related factors. Methods A cross-sectional descriptive study was conducted from January to June 2021 in Hanoi, Vietnam. Ninety-six adult patients with grade 3 and 4 renal failure indicated kidney transplantation had central corneal thickness measured. We investigated the mean value of central corneal thickness in patients with indications for kidney transplantation. The related factors were evaluated by multivariable linear regression. Results The mean thickness of the central cornea in the right eye was 529.3 ± 32 µm, and the left eye was 528.5 ± 32.1 µm, with no difference between the central corneal thickness in the two eyes. Corneal thickness has a positive correlation with IOP after dialysis and smoking habits, adjusted R2 = 0.2405, has a negative correlation with age, adjusted R2 = 0.2405, and with calcium concentration blood, adjusted R2 = 0.032. Conclusion The thickness of the central cornea in patients with renal failure with indications for kidney transplantation in both eyes is similar. Factors related to corneal thickness are age, smoking habits, intraocular pressure after dialysis, and blood calcium levels.

Dry eye rate and its relationship with disease stage in patients with primary hypertension: a cross-sectional study in Vietnam

“…Significantly, the OSDI score gradually increased, and the Schirmer value gradually decreased from the group of hypertensive patients stage I to III, P<0.001 (Table 2). We found that there were some factors related to this result because age, plasma creatinine, and CRP-hs levels increased gradually from the group of patients with stage I to stage III hypertension, P<0.001 (Table 2), that the factors have all been confirmed by previous studies to be related to DEs [20][21][22][23] . In multivariate analysis, we found that advanced age, long duration of hypertension, diabetes mellitus, elevated plasma creatinine, and CRP-hs are independent factors associated with DE in patients with primary hypertension, P<0.01 (Table 4).…”