Purpose: Patients with end-stage renal failure are susceptible to dry eye disease. This study explores the relationship between dry eye disease and influence factors. Patients and Methods:The control group consisted of 57 healthy subjects who were kidney donors. They were of the same age and sex as the kidney transplant recipients. The outcome variable was the dry eye condition of the participants. The Schirmer test confirmed dry eye disease, TBUT (breakup time test), and the Eye Surface Disease Index (OSDI) questionnaire, using linear regression to evaluate the association. Results: The total number of subjects was 146 (89 kidney recipients and 57 kidney donors). When univariate analysis found the level of visual acuity, the age group involved was statistically significant, while the other factors were not statistically significant. In multivariable logistic regression analysis, age (odds ratio: 2.8, p<0.05), smoking history (odd ratio: 0.1, p<0.05), corneal conjunctival calcification (odd ratio: 0.2, p<0.05); central corneal thickness (odd ratio: 1.02, p<0.05) is considered to be an influence factor for disease progression. Conclusion: Age group, smoking history, corneal central thickness, and conjunctival calcification are factors for dry eye disease in patients preparing to receive a kidney. These results reinforce the evidence for multifactorial dry eye disease in patients with renal impairment.

Objectives Central corneal thickness (CCT) is an important biological indicator of eyeball affecting intraocular pressure, which plays a vital role in glaucoma pathology. This study investigated the central corneal thickness in renal failure subjects with indications for kidney transplantation and commented on some related factors. Methods A cross-sectional descriptive study was conducted from January to June 2021 in Hanoi, Vietnam. Ninety-six adult patients with grade 3 and 4 renal failure indicated kidney transplantation had central corneal thickness measured. We investigated the mean value of central corneal thickness in patients with indications for kidney transplantation. The related factors were evaluated by multivariable linear regression. Results The mean thickness of the central cornea in the right eye was 529.3 ± 32 µm, and the left eye was 528.5 ± 32.1 µm, with no difference between the central corneal thickness in the two eyes. Corneal thickness has a positive correlation with IOP after dialysis and smoking habits, adjusted R2 = 0.2405, has a negative correlation with age, adjusted R2 = 0.2405, and with calcium concentration blood, adjusted R2 = 0.032. Conclusion The thickness of the central cornea in patients with renal failure with indications for kidney transplantation in both eyes is similar. Factors related to corneal thickness are age, smoking habits, intraocular pressure after dialysis, and blood calcium levels.

No abstract

To enhance malaria elimination, Vietnam adopted a Reactive Surveillance andResponse (RASR) Strategy in which malaria case notification and investigation must becompleted within 2 days followed by a foci investigation within 7 days. The nationwideperformance of Vietnam’s RASR strategy has yet to be evaluated. This study aims toevaluate the performance and feasibility of RASR in Vietnam, thereby providingrecommendations for improved RASR. Secondary data analysis of nationwide malariacase-based dataset from 2017 to 2021; In Vietnam, there are guidelines and proceduresfor implementation of each step of RASR. Analysis of a total of 12,965 case reports storedin the database for this period, the completeness of case notification on the reportedmonthly aggregated data was very high in both the paper-based (12.463/12.498, 99.7% in2017-2020) and electronic reporting systems (467/467, 100% in 2021 when electronicreporting was introduced); however, there were delays in notification while using thepaper-based system (timely notification – 7.978/12.498, 63.8%). In 2021, thecompleteness (453/467, 97.0%) and timeliness (371/467, 79.4%) of case investigationwere found to be high. Reactive case detection was the major foci investigation response,with fever screening achievement of 88.6% (11.481 / 12.965) and 88.5% (11.471 / 12.965)among index case and neighboring household members respectively. Overall, there waspolicy commitment for implementation of RASR in Vietnam. The completeness andtimeliness of case notification and case investigation were high and improved after theintroduction of the electronic reporting system. More evidence is required for reactivecase detection in defining the screening area or population.

Purpose: Patients with end-stage renal failure are very susceptible to hypertensive retinopathy. This study explores the relationship between hypertensive retinopathy and risk factors.Methods: The 115 patients with end-stage renal failure are indicated for a kidney transplant. The outcome variable was the hypertensive retinopathy condition of the participants. Wong's classification of hypertensive retinopathy. Using linear regression to evaluate the associationResults: According to levels, the rate of retinal damage due to hypertension is 65.22%. When univariate analysis found the level of visual acuity was statistically significant, the other factors were not statistically significant. In multivariable logistic regression analysis, sex (odds ratio: 3.4, p<0.05), hemodialysis (odd ratio: 3.5, p<0.05), visual acuity (odd ratio: 14.0, p<0.05) is considered to be an influence factor for disease progression.Conclusion: Sex, hemodialysis, visual acuity are factors for hypertensive retinopathy in patients preparing to receive a kidney. These results reinforce the evidence for multifactorial hypertensive retinopathy disease in patients with renal impairment.