Assessment of energy expenditure using doubly labeled water, physical activity by accelerometer and reported dietary intake in Japanese men with type 2 diabetes: A preliminary study

Abstract

The aim of the present study was to determine the total energy expenditure, physical activity and dietary intake of men with type 2 diabetes mellitus and control participants without type 2 diabetes mellitus who were matched for age and body mass index. The participants in the present study were 12 well-controlled type 2 diabetes mellitus patients and 10 controls, aged 40-75 years, with a body mass index <30 kg/m . Total energy expenditure under free-living conditions was assessed using the doubly labeled water method, and physical activity was measured using a triaxial accelerometer. Dietary intake was assessed using a self-recorded food intake diary during the measurement period. Participants were instructed to record their dietary intake over 3 days, including 2 weekdays. Total energy expenditure was not significantly different between the groups (P = 0.153), nor were energy (P = 0.969) or macronutrient intakes. In conclusion, when age and body mass index are matched, total energy expenditure and self-reported energy intake are not significantly different between type 2 diabetes mellitus patients and healthy controls.

Factors involved in body weight loss and its maintenance in morbidly obese inpatients

“…Since the mean fasting glucose level in the diabetic patients of the present study (127 mg/dL) was much lower than that in the [20] (~ 180 mg/ dL), such an increased basal metabolic rate may not exist in the diabetic patients of the present study. A recent paper using doubly labeled water method reported that energy expenditure in the diabetic patients (mean HbA1c levels, 6.4%) is not different from that in the non-diabetic subjects [22]. This is consistent with the results of the present study that there would be no significant differences in EWL per day between diabetic and non-diabetic subjects.…”

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“…Similar results were shown in the energy and macronutrient intakes. Consequently, when age and body mass index (BMI) are matched, both groups showed no significant difference in TEE and self-reported energy intake [2]. These findings suggest that the significance of providing CR meal on Japanese T2DM patients may be theoretically in doubt [2].…”

“…However, this figure has been actually estimated to be remarkably lower than the meal intake standards of the Ministry of Health, Labor, and Welfare. diabetic patients [2,3]. Furthermore, several reports were found concerning the efficacy of LCD [4].…”

“…Do diabetic patients have less requirement and/or consumption calorie a day than healthy subjects? There have not found such reports so far [2]. Recently, a report showed that the energy consumption of diabetic patients turned out to be exactly equivalent to healthy subjects by a detailed method called the double-labeled water method [2].…”

Dietary recommendations for type 2 diabetes patients: Lessons from recent clinical and basic research in Asia

“…In addition, obese type 2 diabetes patients (BMI ≥30 kg/m 2 ) show higher hedonic hunger analyzed by the power of food scale compared with non‐obese type 2 diabetes patients; there is a positive linear association between hedonic hunger and poor glycemic control in obese type 2 diabetes patients, but not in non‐obese type 2 diabetes patients. Furthermore, self‐reported energy intake does not differ between healthy individuals and type 2 diabetes patients (BMI <30 kg/m 2 ) with relatively good glycemic control (average glucose levels 117 ± 16 and glycated hemoglobin 6.4 ± 0.5%). These results show that eating breakfast and reducing the energy content of evening meals is important for restraining bodyweight gain and hedonic hunger, and maintenance of good glycemic control in type 2 diabetes patients.…”