Assessment of enthesopathy in patients with acne vulgaris: A case‐controlled trial

Abstract

Acne vulgaris (AV) is an inflammatory condition of the pilosebaceous unit affecting more than 80% of adolescents. The presence of IL17 cells in biopsies of perifollicular infiltrates of acne lesions as well as the abundance of circulating interferon gamma (IFNγ) has led to AV being regarded as a TH-17 related disease. 1 Enthesitis, a hall mark clinical feature of peripheral spondyloarthropathy (SpA) and a frequent manifestation of musculoskeletal conditions, is an inflammation of tendon insertion sites into bones. 2,3 Ultrasound of enthesis is a very important tool for assessment of enthesitis in spondyloarthropathy. A clinical study showed that 161 (98%) of 164 patients with spondyloarthropathy had at least one abnormal enthesis by grayscale ultrasound combined with power