1999
DOI: 10.1016/s0378-5955(99)00003-9
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Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses

Abstract: The common occurrence of hearing loss in both humans and mice, and the anatomical and functional similarities of their inner ears, attest to the potential of mice being used as models to study inherited hearing loss. A large-scale, auditory screening project is being undertaken at The Jackson Laboratory (TJL) to identify mice with inherited hearing disorders. To assess hearing sensitivity, at least five mice from each inbred strain had auditory brainstem response (ABR) thresholds determined. Thus far, we have … Show more

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Cited by 778 publications
(789 citation statements)
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“…In addition, available ABR data show that CE/J and SJL/J strains retain good hearing (at least up to 400 days of age) or may develop a mild hearing loss at or beyond 1 year of age (Zheng et al, 1999). The early onset gravity receptor deficit in the absence of hearing loss (including significant agerelated hearing loss) suggests that selective vestibular dysfunction may occur.…”
Section: Discussionmentioning
confidence: 99%
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“…In addition, available ABR data show that CE/J and SJL/J strains retain good hearing (at least up to 400 days of age) or may develop a mild hearing loss at or beyond 1 year of age (Zheng et al, 1999). The early onset gravity receptor deficit in the absence of hearing loss (including significant agerelated hearing loss) suggests that selective vestibular dysfunction may occur.…”
Section: Discussionmentioning
confidence: 99%
“…While mouse ABR data are available from a number of resources, recording methods often differ among laboratories, making it virtually impossible to group ABR data collected across laboratories. Therefore, the comparison ABR data used herein were collected by the same laboratory using the methods published by Zheng et al (1999). From the individual mouse data, we calculated means and standard deviations for the 32 kHz thresholds of age-and strain-matched mice.…”
Section: Methodsmentioning
confidence: 99%
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