Assessment of high‐sensitivity C‐reactive protein and lipid levels in healthy adults and patients with coronary artery disease, with and without periodontitis – a cross‐sectional study

Abstract

A persistent infection, such as chronic periodontitis, may influence changes in the systemic levels of HsCRP, LDL and HDL, which potentially have an impact on inflammation-associated atherosclerotic processes, such as CAD.

Biochemical and histopathologic analysis of the effects of periodontitis on left ventricular heart tissues of rats

“…This condition leads to lipid metabolism disorders that are characterized by an increase in serum Tcho and LDL levels . In this context, our findings support the view that periodontitis may increase the risk of CVD by affecting lipid profiles associated with an increase in CRP levels . Furthermore, it has been demonstrated that hyperlipidemia increases susceptibility to infection by negatively affecting immune system cells .…”

The Association Between Dental Status and Systemic Lipid Profile and Inflammatory Mediators in Patients After Myocardial Infarction

“…Many authors have demonstrated that CRP concentration is higher in patients with periodontitis and CVD compared to patients with only one of these two disorders [3,16,20,23,24]. This was also confirmed in a meta-analysis by Paraskevas et al [25].…”

“…These outcomes show that both periodontal tissue breakdown (PD) and level of inflammation (bPP) impinge on the lipid serum level. The results of scientific research on LDL-C concentration in the blood of patients with CVD depending on the state of periodontal tissues are ambiguous [16,17]. However, the majority of reports on patients without cardiovascular burden indicate an impact of periodontitis on lipid disorders expressed by elevated levels of LDL-C, TC and TG, and a reduced level of HDL-C [3,[18][19][20].…”

Soft drink consumption and periodontal status in pregnant women

“…The high consumption of soft drinks is associated with increased triglycerides, reduced HDL levels and increased C‐reactive protein, which are metabolic and inflammatory disorders present in periodontal disease …”

“…Periodontal diseases have also been associated with reduced HDL, high triglycerides, hypertension, type 2 diabetes, visceral obesity, metabolic syndrome, and cardiovascular disease …”