Assessment of hormonal activity in patients with premature ejaculation

Canat, Lütfi; Erbin, Akif; Canat, Masum; Dinek, Mehmet; Çaşkurlu, Turhan

doi:10.1590/s1677-5538.ibju.2016.0064

Cited by 19 publications

(12 citation statements)

References 32 publications

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“…Carani et al 15 48 (34 hyperthyroid Rate of hypothyroidism was 1.1% in the general population and 2.5% in the sexual clinic population. Rate of hyperthyroidism was similar in the two populations (3.5 vs 3.4%).…”

Section: Study N Findingsmentioning

confidence: 94%

“…37 In another case-control study of 63 men with PE and 39 controls by Canat et al, no differences in free T3 or free T4 (p>0.05) were observed, but TSH levels were significantly lower in men with PE (p=0.017). 38 Waldinger et al performed an observational study of 620 men with lifelong PE, which was defined as IELT less than 1 minute since first sexual intercourse experience with all partners >90% of the time. The authors observed that rates of hypo-and hyperthyroidism in men with lifelong PE were not significantly different than those in the general population (p>0.05).…”

Section: Premature Ejaculation and Hyperthyroidismmentioning

confidence: 99%

“…14 Specifically, "disruptions in central serotonergic neurotransmission, potent cortical representation of the pudendal nerve, prostatitis, hypersensitivity of the penis, recreational drugs, and hormonal disorders" have been implicated. 15 On the other end of the spectrum is delayed ejaculation (DE), which is more poorly defined and studied. While no specific duration of ejaculatory latency has been agreed upon, a prevailing definition is a complete lack of or delay in ejaculation longer than normal in the setting of appropriate stimulation.…”

Section: Introductionmentioning

confidence: 99%

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Effect of Thyroid Hormone Derangements on Sexual Function in Men and Women

Bates

Kohn

Pastuszak

2020

Sexual Medicine Reviews

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Introduction: Sexual dysfunction affects many people, with 33-60% of women reporting sexual dysfunction and 8-52% of men with erectile dysfunction (ED) or premature ejaculation (PE). In an effort to determine the constellation of factors responsible for sexual dysfunction, the effect of thyroid hormone derangements has been of recent interest. Aim: To investigate the associations between thyroid hormones and sexual dysfunction in women and men. Methods: Review of the literature examining effects of hypo-and hyperthyroidism on sexual function. Main Outcome Measures: Summary of effects of thyroid dysfunction on domains of sexual functioning. Results: Most studies demonstrate that hypothyroid and hyperthyroid men have increased rates of sexual dysfunction, including erectile dysfunction (ED) in hypothyroid men. However, studies vary on the strength of correlation between hormonal derangement and level of sexual dysfunction. In both hyper-and hypothyroid men, treatment of thyroid disorder at least partially reverses sexual dysfunction. In contrast, the current literature provides no consensus on the effect of hypothyroidism, hyperthyroidism, or Hashimoto's thyroiditis on female sexual function. In studies that observed increased rates of sexual dysfunction in women with thyroid disorders, correction of the thyroid derangement resulted in resolution of some sexual dysfunction. Studies are also conflicted on whether there is a relationship between degree of sexual dysfunction and degree of hormone derangement in women. However, prior work has demonstrated a relationship between thyroid autoantibodies and sexual dysfunction in women.

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Section: Study N Findingsmentioning

confidence: 94%

Section: Premature Ejaculation and Hyperthyroidismmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effect of Thyroid Hormone Derangements on Sexual Function in Men and Women

Bates

Kohn

Pastuszak

2020

Sexual Medicine Reviews

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“…PE has always been a worrying condition whose research of the mechanism has raised several theories: psychogenic, neurobiological, genetic and hormonal [6]. Among our respondents (303), 42.2% identified themselves as PE while 57.4% did not.…”

Section: Discussionmentioning

confidence: 85%

Premature Ejaculation in Cotonou

Natchagandé¹,

Avakoudjo²,

Michael³

et al. 2017

Andrology

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Objectives: Premature ejaculation is the most common sexual disorder whose definition is still very controversial. The purpose of this study is to assess its incidence, social impact and support in our population. Methodology: It was a descriptive and cross-cutting study which took place in CNHU HKM and Ménontin district hospital over a period of one month from 15 th May to 15th June 2016. Outcomes: 42.2% of the study population are faced with premature ejaculation. The average age of premature ejaculators was 39.0 years ± 13.5. The average intravaginal ejaculation latency time (IELT) among premature ejaculators was 7.8 min ± 8.4 against 11.95 min ± 8.9 for non-premature ejaculators. 74.9% of respondents' partners were satisfied with the intravaginal ejaculation latency time of their spouse. Only 28.1% of premature ejaculators resorted to treatment at least once to improve their intravaginal ejaculation latency time. Conclusion: Premature ejaculation is a cross-cutting issue in the population but the absence of consensus on its parameters prevents a satisfactory research.

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“…[ 2 ] Recently, the prevalence of PE has been 26.67% according to the study of Benha University. [ 3 ] Several studies suggest that the etiology of PE includes a range of biological and psychological factors such as luteinizing hormone, prolactin, thyroid-stimulating hormone, diabetes, testosterone, [ 4 , 5 ] erectile dysfunction, infertility, lower urinary tract symptoms, and varicocele (VC) also have been recognized as risk factors for PE. [ 6 , 7 ]…”

Section: Introductionmentioning

confidence: 99%

Efficacy of microsurgical varicocelectomy in the treatment of premature ejaculation

Zhang

Yao

et al. 2020

Medicine

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Introduction: Premature ejaculation (PE) is the most common type of sexual disorder among men which comprises a great of problems. Varicocele is defined as the dilation of the pampiniform venous plexus draining the testicle. At present, selective serotonin reuptake inhibitors antidepressants, topical anesthetics, tramadol, phosphodiesterase type 5 inhibitors are the common alternative strategy to improve PE. However, these therapeutic measures have several shortcomings and side effects. Recently, the correlation between varicocele and PE has attracted the attention of some researchers. A few studies consider microsurgical varicocelectomy can be a new remedy for PE. But it is still absent enough a great deal of convincing evidence. The study will assess the effectiveness and safety of the microsurgical varicocelectomy treatment in PE patients. Methods and analysis: Electronic databases including English databases (PubMed, MEDLINE, EMBASE, Web of Science, Cochrane Library) and Chinese databases (China National Knowledge Infrastructure, China Biology Medicine Database, Wanfang Database, VIP Database) will be searched from their inception to December 2020 to recognize related studies. All the randomized controlled trials of microsurgical varicocelectomy for the management of PE patients will be included. The potential outcome will include intravaginal ejaculation latency time, Chinese index of sexual function for premature ejaculation-5, visual analogue score, premature ejaculation diagnostic tool, success treatment rate, serum testosterone levels. We will conduct this study strictly according to the Cochrane Handbook for systematic reviews of interventions. Results: The current study is a protocol for systematic review and meta-analysis without results, and data analysis will be carried out after the protocol. We will share our findings in the February 28, 2021. Conclusion: This systematic review will provide more evidence to assess whether microsurgical varicocelectomy is an effective intervention for patients with PE. The results will be published in a public issue journal and offer the urologists and andrologists help to make clinical decisions. Ethics and dissemination: Formal ethical approval is not required in this protocol. We will collect and analyze data based on published studies, and since there are no patients involved in this study, individual privacy will not be under concerns. The results of this review will be disseminated to peer-reviewed journals or submit to related conferences. Protocol registration number: INPLASY202060058

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Assessment of hormonal activity in patients with premature ejaculation

Cited by 19 publications

References 32 publications

Effect of Thyroid Hormone Derangements on Sexual Function in Men and Women

Effect of Thyroid Hormone Derangements on Sexual Function in Men and Women

Premature Ejaculation in Cotonou

Efficacy of microsurgical varicocelectomy in the treatment of premature ejaculation

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