Assessment of in vitro antioxidant capacity and polyphenolic composition of selected medicinal herbs from Leguminosae family in Peninsular Malaysia

Chew, Yik Ling; Goh, Joo Kheng; Lim, Yau Yan

doi:10.1016/j.foodchem.2009.01.091

Cited by 208 publications

(146 citation statements)

References 25 publications

Supporting

Mentioning

139

Contrasting

Unclassified

Order By: Relevance

“…The method of Chew et al has been used for the scavenging ability of DPPH antioxidant test [9] . A total of 1 mL of different concentrations of diluted extracts of each plant parts in ethanol was added to 1 mL of DPPH (0.15 mmol/L in ethanol) and at the same time, a control consisting on 1 mL DPPH with 1 mL ethanol was prepared.…”

Section: Determination Of Total Flavonoid Contentmentioning

confidence: 99%

Chemical composition and antioxidant activity of a Lebanese plant Euphorbia macroclada schyzoceras

Farhan

Rammal

Hijazi

et al. 2013

Asian Pacific Journal of Tropical Biomedicine

View full text Add to dashboard Cite

Section: Determination Of Total Flavonoid Contentmentioning

confidence: 99%

Chemical composition and antioxidant activity of a Lebanese plant Euphorbia macroclada schyzoceras

Farhan

Rammal

Hijazi

et al. 2013

Asian Pacific Journal of Tropical Biomedicine

View full text Add to dashboard Cite

“…The method of Chew et al [11] has been used for the scavenging ability of DPPH antioxidant test with slight modification, this approach has been done through preparation of 1 mL of various concentrations of diluted extracts and added to 1 mL of DPPH, and also, 1 mL of DPPH with 1 mL of ethanol has been prepared as a control. All solutions were mixed by hand afterward left in the dark for half hour, and finally, the absorbance was taken at 517 nm.…”

Section: Dpph Radical Scavenging Activitymentioning

confidence: 99%

Studying the Cytotoxic and Antioxidant Activities of Crude Extracts From Anacyclus Nigellifolius Boiss Grown in North Lebanon.

Farhan

2018

Asian J Pharm Clin Res

View full text Add to dashboard Cite

Objective: The objective of this study is to evaluate the chemical contents (total phenolic and total flavonoid contents) of the crude ethanolic and aqueous extracts from leaves and stems of a Lebanese plant and to evaluate their cytotoxic and antioxidant activities.Methods: Quantification of the total phenolic and total flavonoid contents of all extracts of Anacyclus nigellifolius from leaves and stems and the cytotoxic activity were evaluated through XTT assay, while antioxidant activities were evaluated using spectrophotometric analyses DPPH, H 2 O 2 , and chelating of ferrous ions tests. Results:The ethanolic extract from leaves and stem of A. nigellifolius was better than aqueous extract and showed a higher content in total phenolic and total flavonoid which was 39.48±0.04 and 13±0.03, respectively. On the other hand, the best value of IC50 of DPPH, H 2 O 2 , and chelating of ferrous ions of ethanol extract from leaves was 0.1 mg/mL, 0.25 mg/mL, and 0.37 mg/mL, respectively, also, ethanol extract has significantly inhibited cells growth 293T and MCF7, a percentage of inhibition was in leaves, and it has reached the 70% and 54%, respectively. Conclusions:Both ethanolic and aqueous extracts of both parts of A. nigellifolius have shown high efficiency and good antioxidant and antiproliferation power. Hence, this plant can be used in the prevention of a number of diseases related to oxidative stress as well as might be used for inhibition of cancer cell line growth.

show abstract

“…The scavenging activity of the extracts or standard was calculated as the percent inhibition of DPPH radical scavenged activity using the formula of the absorbance of control minus the absorbance of sample and divided by the absorbance of control and x100 %. Data were expressed as the IC50 and ascorbic acid equivalent antioxidant capacity (AEAC) based on the formulation of (Chew et al, 2009(Chew et al, , 2011. FRAP assay.…”

Section: Determination Of Tpcmentioning

confidence: 99%

Antioxidant Capacity and Acute Testicular Toxicity of Leucaena leucocephala Aqueous Shoot Tips Plus Young Leaves Extracts

et al. 2016

View full text Add to dashboard Cite

BURAWAT, J.; UABANDIT, N.; SRIPANIDKULCHAI, B.; NUALKAEW, S. & IAMSAARD, S. Antioxidant capacity and acute testicular toxicity of Leucaena leucocephala aqueous shoot tips plus young leaves extracts. Int. J. Morphol., 34(2):514-521, 2016. SUMMARY:This study aimed to determine the antioxidant capacity of the Leucaena leucocephala aqueous shoot tips plus young leaves (LL-spl) extracts among three different fractions (LL-spl 10, 20, and 40 min) and to examine its acute toxicity on male reproductive parameters. The amount of the total phenolics in LL-spl extract was determined using a Folin-Ciocalteu reagent method and its antioxidant capacity was analyzed using 1, 1-diphenyl l-2-picrylhydrazyl radical scavenging and ferric reducing antioxidant powder methods. The LL-spl extract fraction with highest antioxidant capacity was used in animal treating. Male rats were divided into three groups (n= 5); control and groups treated with LL-spl 400 and 600 mg/Kg body weight for consecutive 40 days. The results showed that the LL-spl 40 min fraction possessed the highest antioxidant capacity. In addition, the LL-spl 400 and 600 groups showed no differences in weights of body, testis and epididymis, serum testosterone levels, and expression of testicular steroidogenic acute regulatory (StAR) protein. Significantly, LL-spl extract reduced the weight of seminal vesicle, sperm concentration, and seminiferous diameters compared with control. Moreover, LL-spl extract had adverse effect on testicular histology in inducing of seminiferous atrophy and degeneration including dilated blood vessels in interstitial tissue. It was concluded that although LL-spl extract possessing antioxidant capacity, in short term consumptions, it could be toxic to some male reproductive organs especially damaging testicular tissues.

show abstract

Assessment of in vitro antioxidant capacity and polyphenolic composition of selected medicinal herbs from Leguminosae family in Peninsular Malaysia

Cited by 208 publications

References 25 publications

Chemical composition and antioxidant activity of a Lebanese plant Euphorbia macroclada schyzoceras

Chemical composition and antioxidant activity of a Lebanese plant Euphorbia macroclada schyzoceras

Studying the Cytotoxic and Antioxidant Activities of Crude Extracts From Anacyclus Nigellifolius Boiss Grown in North Lebanon.

Antioxidant Capacity and Acute Testicular Toxicity of Leucaena leucocephala Aqueous Shoot Tips Plus Young Leaves Extracts

Contact Info

Product

Resources

About